Giant hemangioma of the placenta


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Abstract

Background. Placental hemangioma belongs to the group of nontrophoblastic tumors. Case report. The paper gives a case of giant placental hemangioma detected at 32 weeks’ gestation. It also describes the course of labor at 35 weeks of pregnancy. There are computed tomographic, histological, and immunohistochemical data on the born placenta. There are also literature data on histological characteristics of the structure of placental hemangiomas, as well as possible pregnancy and labor complications. It is noted that the obstetric tactics for hemangioma mainly depends on its size and the status of the fetus. Conclusion. An observation of giant placental hemangioma is of interest due to its relative rarity and little knowledge of such tumors concerning their importance for fetal development and possible pregnancy complications. The choice of optimum obstetric tactics of management and delivery for pregnant women with placental hemangioma is of importance.

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About the authors

Ulyana Nikolaevna Tumanova

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: ashegolev@oparina4.ru
researcher of pathoanatomical department

Vyacheslav Michailovich Lyapin

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: v_lyapin@oparina4.ru
pathologist, pathoanatomical department

Aleksandr Ivanovich Shchegolev

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: ashegolev@oparina4.ru
MD, professor, Head of pathoanatomical department

Oleg Radomirovich Baev

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia; I.M. Sechenov First Moscow State Medical University

Email: o_baev@oparina4.ru
MD, Head of maternity department

Andrey Mikhailovich Prikhodko

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: a_prikhodko@oparina4.ru
PhD, physician of maternity department

Ekaterina Aleksandrovna Kozhina

M.V. Lomonosov Moscow State University

student of the 6th year

Zulfiya Sagdullaevna Khodzhaeva

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: z_khodzhaeva@mail.ru
MD, professor, senior researcher

References

  1. Benirschke B., Kaufmann P., Baergen R. Pathology of the human placenta. 5th ed. NewYork: Springer; 2006.
  2. Fox H., Sebire N.J. Pathology of the placenta. 3rd ed. Saunders Elsevier; 2007.
  3. Faye-Petersen O.M., Heller D.S., Joshi V.V. Handbook of placental pathologe. 2nd ed. London, New York: Taylor&Francis; 2006.
  4. Baergen R.N. Manual of pathology of the placenta. 2nd ed. New York: Springer; 2011. doi: 10.1007/978-1-4419-7494-5.
  5. Guschmann M., Henrich W., Entezami M., Dudenhausen J.W. Chorioangioma - new insights into a well-known problem I. Results of a clinical and morphological study of 136 cases. J. Perinat. Med. 2003; 31(2): 163-9. doi: 10.1515/JPM.2003.022.
  6. Guschmann M., Henrich W., Dudenhausen J.W. Chorioangiomas - new insights into a well-known problem II. An immuno-histochemical investigation of 136 cases. J. Perinat. Med. 2003; 31(2): 170-5. doi: 10.1515/ JPM.2003.023.
  7. Мальков П.Г., Гриневич В.Н., Морозова М.А., Зорина Ю.В., Юдина Е.В., Савченко Н.П. Гигантская плацентарная гемангиома (хорангиома). Архив патологии. 2009; 71(3): 37-9. [Malkov P.G., Grinevich V.N., Morozova M.A., Zorina Yu.V., Yudina E.V., Savchenko N.P Giant placental hemangioma (chorangioma). Arhiv patologii. 2009; 3: 37-39. (in Russian)]
  8. Казачков Е.П., Воропаева Е.Е., Семенов Ю.А., Пастернак А.Е., Казачкова Э.А. Гигантская хорангиома плаценты. Архив патологии. 2013; 75(5): 52-4. [Kazachkov E.L., Voropaeva E.E., Semenov Iu.A., Pasternak A.E., Kazachkova E.A. Giant chorioangioma of the placenta. Arhiv patologii. 2013; 5: 52-54. (in Russian)]
  9. Щеголев А.И. Современная морфологическая классификация повреждений плаценты. Акушерство и гинекология. 2016; 4: 14-23. doi: http:// dx.doi.org/10.18565/aig.2016.4.16-23. [Shchegolev A.I. Current morphological classification of damages to the placenta. Akusherstvo i ginekologiya/Obstetrics and gynecology. 2016; 4: 14-23. http://dx.doi.org/10.18565/aig.2016.4.16-23 (in Russian)]
  10. Щеголев А.И., Дубова Е.А., Павлов К.А. Морфология плаценты. М.; 2010. 48с. [Shchegolev A.I., Dubova E.A., Pavlov K.A. The morphology of the placenta. M.; 2010. 48 p. (in Russian)]
  11. Mesia A.F., Mo P., Ylagan L.R. Atypical cellular chorangioma. Arch. Pathol. Lab. Med. 1999; 123(6): 536-8.
  12. Jauniaux E., Zucker M., Meuris S., Verhest A., Wilkin P., Hustin J. Chorangiocarcinoma: an unusual tumour of the placenta. The missing link? Placenta. 1988; 9(6): 607-13.
  13. Trask C., Lage J.M., Roberts D.J. A second case of «chorangiocarcinoma» presenting in a term asymptomatic twin pregnancy: choriocarcinoma in situ with associated villous vascular proliferation. Int. J. Gynecol. Pathol. 1994; 13: 87-91.
  14. Khong T.Y. Chorangioma with trophoblastic proliferation. Virchows Arch. 2000; 436(2): 167-71.
  15. Sepulveda W., Alcalde J.L., Schnapp C., Bravo M. Perinatal outcome after prenatal diagnosis of placental chorioangioma. Obstet. Gynecol. 2003; 102(5, Pt 1): 1028-33.
  16. Ropacka-Lesiak M., Gruca-Stryjak K., Breborowicz G. Nontrophoblastic placental tumors. Neuro Endocrinol. Lett. 2012; 33(4): 375-9.
  17. Wu Z., Hu W. Clinical analysis of 26 patients with histologically proven placental chori-oangiomas. Eur. J. Obstet. Gynecol. Reprod. Biol. 2016; 199: 156-63. doi: 10.1016/j.ejogrb.2015.12.009.
  18. Guschmann M. Großes chorangiom bei HELLP syndrom. Gyn. Praxis. 2002; 26: 325.
  19. Shchyogolev A.I. Vascular endothelial growth factor and its receptors in the placental villi of pregnant patients with pre-eclampsia. Bull. Exp. Biol. Med. 2013; 154(6): 792-5. doi: 10.1007/s10517-013-2058-8.
  20. Bashiri A., Furman B., Erez O., Wiznitzer A., Holcberg G., Mazor M. Twelve cases of placental chorioangioma. Pregnancy outcome and clinical significance. Arch. Gynecol. Obstet. 2002; 266: 53-5.
  21. Zanardini C., Papageorghiou A., Bhide A., Thilaganathan B. Giant placental chorioangioma: natural history and pregnancy outcome. Ultrasound Obstet. Gynecol. 2010; 35(3): 332-6. doi: 10.1002/uog.7451.
  22. Bauer C.R., Fojaco R.M., Bancalari E., Fernandez-Rocha L. Microangiopathic hemolytic anemia and thrombocytopenia in a neonate associated with a large placental chorioangioma. Pediatrics. 1978; 62: 574-7.
  23. Wehrens X.H., Offermans J.P., Snijders M., Peeters L.L. Fetal cardiovascular response to large placental chorioangiomas. J. Perinat. Med. 2004; 32(2): 107-12. doi: 10.1515/JPM.2004.020.
  24. Mancuso A., D’anna R., Corrado F., Cannata M.L. Large placental chorioangioma. Acta Obstet. Gynecol. Scand. 2001; 80(10): 965-6.
  25. Hoeger P.H., Maerker J.M., Kienast A.K., Syed S.B., Harper J.I. Neonatal haemangiomatosis associated with placental chorioangiomas: report of three cases and review of the literature. Clin. Exp. Dermatol. 2009; 34(5): e78-80. doi: 10.1111/j.1365-2230.2009.03221.x.
  26. Jauniaux E., Ogle R. Color Doppler imaging in the diagnosis and management of chorioangiomas. Ultrasound. Obstet. Gynecol. 2000; 15(6): 463-7. doi: 10.1046/j.1469-0705.2000.00127.x.
  27. Abramowicz J.S., Sheiner E. In utero imaging of the placenta: importance for diseases of pregnancy. Placenta. 2007; 28(Suppl. A): S14-22. doi: 10.1016/j. placenta.2007.02.004.
  28. Wei S.H., Helmy M., Cohen A.J. CT evaluation of placental abruption in pregnant trauma patients. Emerg. Radiol. 2009; 16(5): 365-73. doi: 10.1007/ s10140-009-0804-z.
  29. Kani K.K., Lee J.H., Dig M., Moshiri M., Kolokythas O., Dubinsky T. Gestatational tropho-blastic disease: multimodality imaging assessment with special emphasis on spectrum of abnormalities and value of imaging in staging and management of disease. Curr. Probl. Diagn. Radiol. 2012; 41(1): 1-10. doi: 10.1067/j.cpradiol.2011.06.002.
  30. Sepulveda W., Wong A.E., Herrera L., Dezerega V., Devoto J.C. Endoscopic laser coagulation of feeding vessels in large placental chorioangiomas: report of three cases and review of invasive treatment options. Prenat. Diagn. 2009; 29(3): 201-6. doi: 10.1002/pd.2197.
  31. Nicolini U., Zuliani G., Caravelli E., Fogliani R., Poblete A., Roberts A. Alcohol injection: a new method of treating placental chorioangiomas. Lancet. 1999; 353(9165): 1674-5. doi: 10.1016/ S0140-6736(99)00781-3.

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