PREECLAMPSIA AND LOWER MATERNAL MORTALITY IN RUSSIA


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Objective. To study the most important aspects of maternal mortality from preeclampsia, eclampsia, the current clinical features of the most severe forms of this complication of pregnancy, as well as main defects in rendering qualified medical care, including those in the development of complications. Subjects and methods. A confidential audit of maternal mortality was conducted in different regions of the Russian Federation in 2013-2015. A total of 270 anonymous copies of primary medical records were analyzed. Results. The features of development and progression of the most severe forms of preeclampsia and eclampsia were identified. The development of preeclampsia in the presence of previous extragenital diseases was seen in most clinical cases. Early clinical manifestation is characteristic in the vast majority of women; and the non-classical (atypical) clinical picture of the disease is also common. Conclusion. Practical activities are proposed, which are aimed at reducing maternal mortality from preeclampsia in Russia.

Full Text

Restricted Access

About the authors

Iraida Stepanovna Sidorova

Academician of RAS, MD, Professor, Professor of Departament of Obstetrics and Gynecology № 1, Honoured Scientist of the Russian Federation, I.M. Sechenov First Moscow State Medical University, Therapeutic Faculty. 119991 Moscow, Russia, Trubetskaya str., 8, build. 2

Natalya Aleksandrovna Nikitina

Email: natnikitina@list.ru
MD, Associate Professor of Departament of Obstetrics and Gynecology № 1, I.M. Sechenov First Moscow State Medical University, Therapeutic Faculty 119991 Moscow, Russia, Trubetskaya str., 8, build. 2

Ara Leonidovich Unanyan

Email: 9603526@mail.ru
MD, Professor, Professor of Departament of Obstetrics and Gynecology № 1, I.M. Sechenov First Moscow State Medical University, Therapeutic Faculty. 119991 Moscow, Russia, Trubetskaya str., 8, build. 2

References

  1. Филиппов О.С., Гусева Е.В., Малышкина А.И., Михайлов А.В., Линде В.А., Зубенко Н.В., Фаткуллин И.Ф., Башмакова Н.В., Артымук Н.В., Пестрикова Т.Ю. Материнская смертность в Российской Федерации в 2015 году. Методическое письмо Министерства здравоохранения Российской Федерации № 15-4/10/2-6810 от 28.10.2016. 85с. [Filippov O.S., Guseva E.V., Malyshkina A.I., Mikhailov A.V., Linde V.A., Zubenko N.V., Fatkullin I.F., Bashmakova N.V., Artymuk N.V., Pestrikova T. Yu. Maternal mortality in the Russian Federation in 2015. Methodical letter of the Ministry of Health of the Russian Federation No. 15-4/10/2-6810 of October 28, 2016. 85p. (in Russian)]
  2. Филиппов О.С., Гусева Е.В., Сидорова И.С., Никитина Н.А. Материнская смертность в Российской Федерации: анализ официальных данных и результаты конфиденциального аудита в 2013 году. Методическое письмо Министерства здравоохранения Российской Федерации № 15-4/10/2-7509 от 02.10.2014. 91с. [Filippov O.S., Guseva E.V., Sidorova I.S., Nikitina N.A. Maternal mortality in the Russian Federation: analysis of official data and the results of confidential audit in 2013. Methodical letter of the Ministry of Health of the Russian Federation No. 15-4/10/2-7509 of 02.10.2014. 91p. (in Russian)]
  3. Ходжаева З.С., Коган Е.А., Клименченко Н.И., Акатьева А.С., Сафонова А.Д., Холин А.М., Вавина О.В., Сухих Г.Т. Клинико-патогенетические особенности ранней и поздней преэклампсии. Акушерство и гинекология. 2015; 1: 12-7. [Khodzhaeva Z.S., Kogan E.A., Klimenchenko N.I., Akatyeva A.S., Kholin A.M., Vavina O.V. , Sukhikh G.T. Clinical and pathogenetic features of early and late preeclampsia. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2015; 1: 12-7. (in Russian)]
  4. Шалина Р.И., Курцер М.А., Штабницкий А.М., Курганская М.А., Платицын И.В. Синдром задней обратимой энцефалопатии в течении атипичной преэклампсии и эклампсии. Акушерство и гинекология. 2017; 1: 89-93. http://dx.doi.org/10.18565/aig.2017.L89-93 [Shalina R.I., Kurtser M.A., Shtabnitsky A.M., Kurganskaya M.A., Platitsyn I.V. Posterior reversible encephalopathy syndrome during atypical preeclampsia and eclampsia. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2017; (1): 89-93. (in Russian) http://dx.doi.org/10.18565/aig.2017.1.89-93]
  5. Сидорова И.С., Никитина Н.А. Особенности патогенеза эндотелиоза при преэклампсии. Акушерство и гинекология. 2015; 1: 72-8. [Sidorova I.S., Nikitina N.A. Pathogenesis of endotheliosis in preeclampsia. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2015; 1: 72-8. (in Russian)]
  6. Козловская Н.Л., Прокопенко Е.И., Эмирова Х.М., Серикова С.Ю. Клинические рекомендации по диагностике и лечению атипичного гемолитико-уремического синдрома. Нефрология и диализ. Репринт. 2015; 17(3). 24с. [Kozlovskaya N.L., Prokopenko E.I., Emirova Kh.M., Serikova S.Yu. Clinical recommendations for the diagnosis and treatment of atypical hemolytic-uremic syndrome. Nefrologiya i dializ. The reprint. 2015; 17 (3). 24p. (in Russian)]
  7. Макацария А.Д., Бицадзе В.О., Хизроева Д.Х., Акиньшина С.В. Тромботические микроангиопатии в акушерской практике. М.: ГЭОТАР-Медиа; 2017. 304с. [Makatsariya A.D., Bitsadze V.O., Khizroeva D.Kh., Akinshina S.V. Thrombotic microangiopathies in obstetric practice. Moscow: GEOTAR-Media; 2017. 304p. (in Russian)]
  8. Макацария А.Д., Акиньшина С.В., Бицадзе В.О. Преэклампсия и HELLP-синдром как проявление тромботической микроангиопатии. Акушерство и гинекология. 2014; 4: 4-10. [Makatsaria A.D., Akinshina S.V., Bitsadze V.O. Preeclampsia and HELLP syndrome as a manifestation of thrombotic microangiopathy. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2014; 4: 4-10. (in Russian)]
  9. Калачин К.А., Пырегов А.В., Федорова Т.А., Грищук К.И., Шмаков Р.Г. «Нетипичный» HELLP-синдром или атипичный гемолитико-уремический синдром? Акушерство и гинекология. 2017; 1: 94-102. http://dx.doi. org/10.18565/aig.2017.1.94-102 [Kalachin K.A., Pyregov A.V., Fedorova T.A., Grishchuk K.I., Shmakov R.G. Atypical HELLP syndrome or atypical hemolytic uremic syndrome? Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2017; (1): 94-102. (in Russian) http://dx.doi.org/10.18565/aig.2017.1.94-102]
  10. Pérez-Calatayud A.A., Briones-Garduno J.C., Álvarez-Goris Mdel P., Sánchez Zamora R., Torres Aguilar A.A., Mendoza-Morales R.E. Atipical uremic hemolityc syndrome in pregnancy. Cir. Cir. 2016; 84(4): 344-9.
  11. Campistol J.M., Arias M., Ariceta G., Blasco M., Espinosa L., Espinosa M. et al. An update for atypical haemolytic uraemic syndrome: diagnosis and treatment. A consensus document. Nefrologia. 2015; 35(5): 421-47.
  12. Blasco Pelicano M., Rodriguez de Córdoba S., Campistol Plana J.M. Atypical hemolytic uremic syndrome. Med. Clin. (Barcelona). 2015; 145(10): 438-45.
  13. Barbour T., Johnson S., Cohney S., Hughes P. Thrombotic microangiopathy and associated renal disorders. Nephrol. Dial. Transplant. 2012; 27(7): 2673-85.
  14. Erémeaux-Bacchi V., Eakhouri E., Roumenina L., Dragon-Durey M.A., Loirat C. Atypical hemolytic-uremic syndrome related to abnormalities within the complement system. Rev. Med. Interne. 2011; 32(4): 232-40.
  15. Noris M., Caprioli J., Bresin E., Mossali C., Pianetti G., Gamba S. et al. Relative role of genetic complement abnormalities in sporadic and familial aHUS and their impact on clinical phenotype. Clin. J. Am. Soc. Nephrol. 2010; 5(10): 1844-59.
  16. Loirat C., Erémeaux-Bacchi V. Atypical hemolytic uremic syndrome. Orphanet J. Rare Dis. 2011 Sep 8; 6: 60.
  17. Сухих Г.Т., Мурашко Л.Е. Преэклампсия. Руководство. М.: ГЭОТАР-Медиа; 2010. 576с.
  18. Сухих Г.Т., Ванько Л.В. Иммунные факторы в этиологии и патогенезе осложнений беременности. Акушерство и гинекология. 2012; 1: 128-36. [Sukhikh G.T., Vanko L.V. Immune factors in the etiology and pathogenesis of pregnancy complications. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2012; 1: 128-36. (in Russian)]
  19. Кирсанова Т.В., Виноградова М.А., Федорова Т.А. Имитаторы тяжелой преэклампсии и HELLP-синдрома: различные виды тромботической микроангиопатии, ассоциированной с беременностью. Акушерство и гинекология. 2016; 12: 5-14. http://dx.doi.org/10.18565/aig.2016.12.5-14 [Kirsanova T.V., Vinogradova M.A., Fedorova T.A. The imitators of severe preeclampsia and HELLP syndrome: Different types of pregnancy-associated thrombotic microangiopathy. Akusherstvo i Ginekologiya/Obstetrics and Gynecology. 2016; (12): 5-14. (in Russian) http://dx.doi.org/10.18565/ aig.2016.12.5-14]

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies