Human umbilical cord tissue cryopreservation: prospects for clinical application


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Abstract

The paper analyzes the data available in the modern scientific literature on the possibility of human umbilical cord tissue cryopreservation and its further clinical application. It describes protocols to obtain various biomedical products (vascular matrix, Wharton jelly-based grafts, and multipotent stromal cells) from the frozen umbilical cord, as well as prospects of their clinical use. The analysis of the literature data may be indicative of the active development of a promising cell biotechnology area, such as human umbilical cord cryopreservation.

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About the authors

Svetlana O. Strokova

Academician V.l. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: estel.7@list.ru
doctor of the clinical laboratory diagnostics laboratory for the collection and storage of biomaterials

Irina V. Arutyunyan

Academician V.l. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia; Research Institute of Human Morphology

Email: labrosta@yandex.ru
PhD, senior researcher, Laboratory of Regenerative Medicine; Senior researcher

Svetlana M. Mullabaeva

Academician V.l. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: s_mullabaeva@oparina4.ru
head of the laboratory for the Collection and Storage of Biomaterials

Timur Kh. Fatkhudinov

Academician V.l. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia; Research Institute of Human Morphology

MD, head of the Laboratory of Regenerative Medicine; Professor of the Department of Histology, Cytology and Embryology, Medical Institute

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