Uterine fibroids as a risk factor for tubal infertility
- Authors: Brodsky G.V.1, Adamyan L.V.2, Sukhikh G.T2
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Affiliations:
- Obstetrics and Gynecology Clinic
- National Medical Research Center of Obstetrics, Gynecology, and Perinatology named after Academician V.I. Kulakov, Ministry of Health of Russia
- Issue: No 10 (2018)
- Pages: 92-99
- Section: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/248315
- DOI: https://doi.org/10.18565/aig.2018.10.92-98
- ID: 248315
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Abstract
Objective. To identify the regularities of macro/microscopic changes in the uterine tube wall in uterine fibroids with a submucosal and/or intramural nodule. Subjects and methods. A retrospective, comparative study was conducted to examine the morphological status of histological specimens of 100 fallopian tubes in 50 reproductive-aged women through histological, immunohistochemical, and morphometric examinations. Results. The findings were analyzed taking into account the assessment of structural elements in different parts of the fallopian tube, the thickness of its wall layers, the characteristics of arterial and venous blood supply and microarchitecture of the fallopian tube wall in different phases of the ovarian and menstrual cycle in concomitant submucosal and intramural uterine fibroids. The findings were compared with the histological and morphometric data of the control group, without indicating the presence of concomitant genital pathology in the clinical protocol. Conclusion. The finding may lead to the conclusion that the observed changes in the fallopian tube wall in uterine myoma play an important role as a morphological substrate for the clinical data related to the low efficiency of assisted reproductive technologies. This study makes it possible to clarify a diagnostic algorithm and management tactics for patients with uterine myoma in an infertility clinic.
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About the authors
Gregory V. Brodsky
Obstetrics and Gynecology Clinic
Email: I50665@gmx.net
MD, Specialist Obstetrics and Gynaecology, Head of Practice Munich, Germany
Leila V. Adamyan
National Medical Research Center of Obstetrics, Gynecology, and Perinatology named after Academician V.I. Kulakov, Ministry of Health of RussiaMD, professor, academician of RAS; deputy director on science, head of department of operative gynecology
G. T Sukhikh
National Medical Research Center of Obstetrics, Gynecology, and Perinatology named after Academician V.I. Kulakov, Ministry of Health of Russia
Email: g_sukhikh@oparina4.ru
MD, PhD, Professor, Academician of Russian Academy of Sciences, Director
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