Evaluation of human papillomavirus infection in women in the Lipetsk Region, by using a diagnostic self-sampling test


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Abstract

Objective. To improve cervical cancer screening programs via clinical introduction of a diagnostic vaginal swab self-sampling test for the detection of high-risk human papillomavirus (hrHPV). Subjects and methods. A total of 455 residents of the Lipetsk Region were examined; vaginal swabs tested for HPV were taken both independently by a woman with a Qvintip device and by a gynecologist with a universal urogenital probe. The women were asked whether it was convenient for them to self-collect a vaginal swab. Results. In the surveyed sample of 455 women, there were 35 (7.7%) cases of hrHPV identified on the swabs collected by the Qvintip and 38 (8.4%) women with hrHPV detected on those taken by the physician, out of them 26 (68.5%) women had atypical squamous cells of undetermined significance. 70.3% of women preferred the Qvintip self-sampling method. Conclusion. The Qvintip self-sampling method for hrHPVtesting shows high diagnostic efficiency, simplicity, and ease-to-use. The method may be recommended for the detection of hrHPV to increase cervical cancer screening coverage.

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About the authors

Inna A. Apolikhina

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia; I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia

Email: i_apolikhina@oparina4.ru
MD, head of the Department of Aesthetic Gynecology and Rehabilitation; Professor of the Department of Obstetrics, Gynecology and Perinatology

Lala K. Bashirova

I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia

Email: leyla9296@hotmail.com
competitor of a scientific degree of candidate of science

Lyudmila I. Letnikova

Healthcare Department of the Lipetsk Region

deputy head of administration of the Lipetsk region

Olga V. Khudyakova

Healthcare Department of the Lipetsk Region

consultant of the department of organization of medical care for children and the obstetric aid service of the health department of the Lipetsk region

Sergey A. Ivanov

Healthcare Department of the Lipetsk Region

head of the department of organization of medical care for children and the obstetric aid service of the health department of the Lipetsk region

Elena A. Gorbunova

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

obstetrician-gynecologist, physiotherapist of the Department of Aesthetic Gynecology and Rehabilitation

Natalia V. Dolgushina

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

MD, head of the department of scientific planning and audit

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