Low-grade intraepithelial cervical lesions in pregnant women with HPV and vaginal biocenotic disorders


Дәйексөз келтіру

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Аннотация

The authors have established a relationship between intraepithelial cervical lesions and vaginal biocenotic disorders in pregnant women with human papillomavirus (HPV) infection and determined their management tactics. The HPV-positive pregnant women have a high incidence of vaginal dysbiosis (38.7%) that is, in most of them, characterized by co-infection (65%), mainly by anaerobic and aerobic infections (44.1%). High-rate HPV in the pregnant women is associated with bacterial vaginosis, mixed dysbiosis, and their recurrences and with the frequency of atypical squamous cells of undetermined significance (ASCUS) and low-grade squamous intraepithelial lesions (LSIL) in the presence of an inflammatory response. Restoring the normal microflora contributes to the disappearance of the inflammatory response and to the reduction of ASCUS. Therapy for dysbiosis does not change the rate of LSIL at 3-month follow-up.

Толық мәтін

Рұқсат жабық

Авторлар туралы

Tamara Bebneva

Peoples' Friendship University of Russia

Email: bebn@mail.ru
Candidate of Medical Sciences, Associate Professor of the Department of Obstetrics, Gynecology and Reproductive Medicine, Faculty of Advanced Training for Medical Professionals of the Medical Institute

Galina Dikke

F.I. Inozemtsev Academy of Medical Education

Email: galadikke@yandex.ru
doctor of medical sciences, associate professor, Professor of the Department of Obstetrics and Gynecology with a course of reproductive medicine

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