Fluorescence hysteroresectoscopy in the clarifying diagnosis of early endometrial cancer


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Abstract

Objective. To acquaint practitioners with a fluorescence hysteroresectoscopy technique in improving the diagnosis of atypical hyperplasia and early endometrial cancer. Material and methods. The paper describes the fluorescence hysteroresectoscopy technique performed at the Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia. Results. Fluorescence hysteroresectoscopy makes it possible to identify the topography of neoplasia and the selectivity of photosensitizer (5-ALA) accumulation in tumor tissue and to perform a targeted biopsy from the maximum fluorescence foci for histological verification. Conclusion. The introduction of fluorescence hysteroresectoscopy in clinical practice will be able to assess the possibility and success of organ-sparing treatment (hormone therapy) in reproductive-aged women, to monitor the endometrial status, and to timely diagnose a recurrence during or after hormone therapy in patients with early endometrial cancer.

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About the authors

Stanislav M. Pronin

National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov Ministry of Health of Russia

Email: psm_doc@mail.ru
PhD, oncologist, obstetrician-gynecologist, senior Researcher of Department of Innovative Oncology and Gynecology

Irina A. Matsneva

I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: via.white.doc@gmail.com
student of the 6th year medical faculty

Muslim R. Maltsagov

National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov Ministry of Health of Russia

Email: terekman94@gmail.com
clinical resident of Ith year

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