Risk factors for gestational diabetes mellitus


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Abstract

Objective. To identify significant risk factors for developing gestational diabetes mellitus (GDM) in women with hypothalam ic dysfunction (HD) and metabolic disorders of puberty for predicting adverse pregnancy outcomes. Materials and methods This prospective study of 170 female adolescents with HD in puberty was conducted from 2000 to 2014. Seventy-two pregnant women with a history of HD were examined for socioeconomic and biomedical risk factors of GDM. Relative risk (RR) and 95% confidence interval (95%CI) were used to estimate the effects of specific risk factors. Results The predictors with the best accuracy for predicting the probability of developing GDM were diabetes mellitus among family members (OR = 5.6) and induced pregnancy (OR = 1.4). Conclusions. Women with a history of HD and metabolic disorders, who plan to use assisted reproductive technologies to treat infertility, should be considered a high-risk group for GDM.

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About the authors

Irina V. Zhutovets

Amur State Medical Academy of Minzdrav of Russia

Email: zhukovec040875@mail.ru
PhD, head of the Department of Obstetrics and Gynecology

Sergey A. Levakov

I.M. Sechenov First Moscow State Medical University of Minzdrav of Russia (Sechenov University)

Email: levakoff@yandex.ru
MD, head of the Department of Obstetrics and Gynecology

Olga Ya. Leshchenko

Scientific Center of Family Health Problems and Human Reproduction

Email: loyairk@mail.ru
MD, chief researcher

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