Umbilical cord blood acid-base balance and gas composition in relation to the use of epidural analgesia in vaginal delivery


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Objective. To study the parameters of umbilical cord blood acid-base balance and gas composition in relation to the use of epidural analgesia (EA) in childbirth. Subjects and methods. The investigation enrolled 380 women; a study group (n = 188) received no EA; a comparison group (n = 192) had EA. The parameters of umbilical cord blood acid-base balance and gas composition were determined using a gas analyzer. Results. The pH values in the EA and non-EA groups were 7.28 (0.06) and 7.31 (0.07), respectively (p = 0.02). In these groups, Base Excess (BE) was 8.3 (2.3) and 6.7 (1.7), respectively (p = 0.004). The partial pressure of oxygen and carbon dioxide did not differ. Conclusion. EA in childbirth does not have a clinically significant negative effect on the fetus and newborn, but is combined with a decrease in pH (p = 0.02) and an increase in the level of BE deficiency (p = 0.004)

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作者简介

Oleg Tysyachnyy

National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov Ministry of Health of Russia

Email: olti23@mail.ru
PhD, scientific researcher of the first maternity departments

Oleg Baev

National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov Ministry of Health of Russia

Email: metod_obsgyn@hotmail.com
MD, professor, head of the first Maternity Department

Aleksandra Evgrafova

National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov Ministry of Health of Russia

Email: a_evgrafova@oparina4.ru
second year postgraduate student of the first Maternity Department

Andrey Prikhodko

National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov Ministry of Health of Russia

Email: a_prikhodko@oparina4.ru
PhD, physician of the first Maternity Department

Sergey Pismensky

National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov Ministry of Health of Russia

Email: s_pismensky@oparina4.ru
assistant of the Department of Anesthesiology and Resuscitation

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