Lipidomic markers and prospects for their use in human papillomavirus-associated cervical diseases


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Abstract

Modern medicine has great potential for searching for new rapid methods for the early diagnosis of precancerous diseases of the cervix andfor identifying a group at risk for recurrent processes after surgical treatment for cervical intraepithelial neoplasias. New and intensively developing science areas, such as metabolomics, lipidomics, and proteomics, are now being widely discussed. The review is dedicated to the analysis of lipidome in breast cancer, endometriosis, and neoplastic changes in cervical tissues by mass spectrometry as a highly informative method to search for biomarkers of human papillomavirus (HPV)-associated cervical diseases.

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About the authors

D. I Attoeva

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology

Email: attoevadjamilya@gmail.com

N. M Nazarova

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology

Email: grab2@yandex.ru

N. L Starodubtseva

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology

Email: n_starodubtseva@oparina4.ru

V. V Chagovets

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology

Email: vvchagovets@gmail.com

V. E Frankevich

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology

Email: v_frankevich@oparina4.ru

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