Catastrophic antiphospholipid syndrome and thromboses


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Abstract

The authors have carried out a systematic analysis of data on the pathogenesis and clinical manifestations of catastrophic antiphospholipid syndrome (APS). The review includes data from foreign and Russian articles published in the past 10years and found in e-Library and PubMed on this topic. It presents data on the pathogenesis, diagnosis, including differential one, and treatment of catastrophic APS. Risk factors for catastrophic APS should be carefully assessed for any pregnant woman who has any of these signs/symptoms: multiple organ thromboses and suspicious laboratory findings, which is present in a history of APS.

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About the authors

Aleksander Davidovich Makatsariya

The First I.M. Sechenov Moscow State Medical University

Email: gemostasis@mail.ru
MD, PhD, corresponding member of the Russian Academy of Sciences, Professor, Head of the Department of Obstetrics and Gynecology

Vladimir N. Serov

Research Center for Obstetrics, Gynecology, and Perinatology

Email: v_serov@oparina4.ru
MD, PhD, Professor, Academician of the Russian Academy of Sciences, Principal Researcher

Jean Christophe Gris

Universit de Montpellier; The First I.M. Sechenov Moscow State Medical University

Email: jean.christophe.gris@chu-nimes.fr
MD, PhD, Professor of the Department of Haematology, Centre Hospitalier Rgional; professor of the Department of Obstetrics and Gynecology

Andrei S. Shkoda

L.A. Vorokhobov City Clinical Hospital No.67, Moscow Department of Health

Email: 67gkb@mail.ru
MD, professor, chief physician

Kristina Grigoryeva

The First I.M. Sechenov Moscow State Medical University

Email: grigkristik96@gmail.com
student of paediatric faculty

Marat Mingalimov

The First I.M. Sechenov Moscow State Medical University

Email: ya.mingalimov2017@yandex.ru
student of paediatric faculty

Viktoria Omarovna Bitsadze

The First I.M. Sechenov Moscow State Medical University

Email: gemostasis@mail.ru
MD, PhD, Professor of the Russian Academy of Sciences, Professor of the Department of Obstetrics and Gynecology

Jamilya Khizrievna Khizroeva

The First I.M. Sechenov Moscow State Medical University

Email: gemostasis@mail.ru
MD, PhD, Professor of the Department of Obstetrics and Gynecology

Alexander Viktorovich Vorobyev

The First I.M. Sechenov Moscow State Medical University

Email: alvorobev@gmail.com
MD, PhD, Associate Professor of the Department of Obstetrics and Gynecology

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