Premature birth: past restrictions and new opportunities


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Abstract

The data available in the world literature on studies of infection and inflammation as a factor that leads to premature birth have been sought and analyzed. Premature birth is the central problem of modern obstetrics, the leading cause of perinatal and infant morbidity and mortality. New potential methods for the diagnosis of spontaneous premature birth and preterm amniorrhea, as well as the basic stages of the pathogenesis of this process have been analyzed in detail. Diagnostic transabdominal ultrasound-guided amniocentesis should be considered as an important element in the diagnostic verification of threatening and imminent preterm births with subsequent correction of their obstetric management according to the findings.

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About the authors

Ksenia A. Gorina

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology Ministry of Health of Russia

Email: k_gorina@oparina4.ru
Junior researcher the Department of Pregnancy Pathology 117997, Russia, Moscow, Akademika Oparina str. 4

Zulfiya S. Khodzhaeva

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology Ministry of Health of Russia

Email: zkhodjaeva@mail.ru
M.D., Professor, Head of High Risk Pregnancy Dept 117997, Russia, Moscow, Akademika Oparina str. 4

Dmitry M. Belousov

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology Ministry of Health of Russia

Email: d_belousov@oparina4.ru
ultrasound department specialist 117997, Russia, Moscow, Akademika Oparina str. 4

Igor I. Baranov

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology Ministry of Health of Russia

Email: i_baranov@oparina4.ru
M.D., Professor, Head of science-education department 117997, Russia, Moscow, Akademika Oparina str. 4

Yael A. Gokhberg

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology Ministry of Health of Russia

Email: dr.yaelgokhberg@gmail.com
clinical resident 117997, Russia, Moscow, Akademika Oparina str. 4

Alexander A. Pashchenko

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology Ministry of Health of Russia

Email: al.pashenko20l8@gmail.com
clinical resident 117997, Russia, Moscow, Akademika Oparina str. 4

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