THE VALUE OF FOLATES FOR CHILD HEALTH AND DEVELOPMENT


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Abstract

The literature review describes a modern view on the metabolism of folates and folic acid in the human body and their role in the development of a child. It presents studies used to diagnose folate deficiency. The authors discuss the sequelae of folate deficiency and folic acid excess in pregnant women and newborn infants. They analyze data on the folate status of premature babies. Existing studies show that there is no risk of folate deficiency in premature infants receiving the current feeding regimens, and uncontrolled additional prescription of folic acid can lead to its excessive intake and excessive blood concentrations in premature infants.

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About the authors

Marina Viktorovna Narogan

Academician V. I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia; I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia

Email: m_narogan@oparina4.ru
MD, Leading Researcher, Department of Pathology of Newborn and Premature Infants; Professor, Department of Neonatology 4, Academician Oparin St., Moscow 117997, Russia; 8, Trubetskaya St., Build. 2, Moscow 119991

Valentina Vladimirovna Lazareva

I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia

Email: l_tifl@mail.ru
Postgraduate Student, Department of Neonatology 8, Trubetskaya St., Build. 2, Moscow 119991

Irina Ivanovna Ryumina

Academician V. I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: i_ryumina@oparina4.ru
MD, Head, Department of Pathology of Newborn and Premature Infants 4, Academician Oparin St., Moscow 117997, Russia

Irina Aleksandrovna Vedikhina

Academician V. I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: i_vedikhina@oparina4.ru
Biologist, Clinical Diagnostic Laboratory 4, Academician Oparin St., Moscow 117997, Russia

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