CLINICAL AND ANAMNESTIC FEATURES OF WOMEN WITH PRETERM PREMATURE RUPTURE OF MEMBRANES


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Abstract

Objective. To identify clinical and anamnestic risk factors in pregnant women with preterm premature rupture of membranes Subjects and methods. Examinations were made in 150 women aged 18 to 40 years, who were divided into 3 groups: 1) 50 pregnant women with premature rupture of membranes (PROM); 2) 50 pregnant women with intact membranes, who delivered at 22-36 weeks’ gestation; 3) 50 pregnant women who delivered spontaneously at term (at 5 37 weeks). The age indicators, the history of somatic and gynecological diseases, the outcomes of previous pregnancies, the features of the course of this pregnancy, childbirth and neonatal outcomes were studied in detail. Results. The risk of PROM significantly more often occurred at the most active reproductive age (25-30 years) in primigravida primiparous women who were somatically burdened with frequent respiratory and odontogenic inflammatory diseases. Pregnant women with PROM had several risk factors that occurred during this pregnancy. Cervical diseases and uterine fibroid were statistically significantly more common. The gestational age for PROM varied within 22-36 weeks’ gestation, and the statistically significantly more common method of delivery was cesarean section. In the same group of women, the newborn infants had a birth weight of less than 2500g, which affected neonatal outcomes. Conclusion. The etiology of PROM during preterm pregnancy is multifactorial; there is a need for timely detection, the correction of one or another condition not only during, but also before pregnancy, and the elaboration of strategies for improving the outcomes, by predicting, preventing, and treating this situation.

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About the authors

Gulnara E. Guseynova

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: marysca666@rambler.ru
graduate student in the Department of Pregnancy Pathology 117997 Russia, Moscow, Akademika Oparina str., 4

Zulfiya S. Khodzhaeva

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: zkhodjaeva@mail.ru
M.D., Professor, Head of High Risk Pregnancy Dept 117997 Russia, Moscow, Akademika Oparina str., 4

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