Comparative analysis of techniques for diagnosing retrocervical endometriosis


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Abstract

Objective. To estimate the diagnostic informative value of instrumental examinations in patients with retrocervical endometriosis (RCE). Subjects and methods. According to the extent of RCE and a concurrence of pelvic organ diseases, 120 patients were divided into 4 subgroups: IA) 30patients with RCE; IB) 30patients with RCE and with colon involvement; IC) 30 patients with RCE and endometrioid ovarian cyst; ID) 30 patients with RCE concurrent with uterine myoma. The extent of RCE was determined according to the data of gynecological examination, transvaginal ultrasound (TVUS), MRI, magnetic resonance imaging (MRT), colonoscopy, laparoscopy, and histological examination of surgical material. Results. TVUS was more informative in endometrioid ovarian cysts (95%) and intestinal lesions (87.3%) than in the isolated form of RCE (68.75%). MRI had the highest diagnostic value in identifying endometrioid infiltrates spreading to the intestinal wall (98.6%), or ovarian lesions (97.4%). The sensitivity of TVUS and MRI in uterine fibroids concurrent with RCE was 36.6% and 89.6%, respectively. Both TVUS and MRI in unobvious pelvic adhesions were uninformative (29.13% and 59.23%, respectively). Conclusion. Only laparoscopy enables full visualization of a pathological focus and access to organs. One should not deemphasize the role of preoperative examination including TVUS, MRI, and colonoscopy. Each of the techniques has its own diagnostic value and does not replace, but provides additional information.

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About the authors

I. K Almova

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: www.gold11@mail
postgraduate student of the Surgery Department 117997, Russia, Moscow, Ac. Oparina str. 4

E. G Khilkevich

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: e_khilkevich@oparina4.ru
MD, obstetrician-gynecologist of the Surgery Department 117997, Russia, Moscow, Ac. Oparina str. 4

V. D Chuprynin

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: v_chuprynin@oparina4.ru
PhD, Head of the Surgery Department 117997, Russia, Moscow, Ac. Oparina str. 4

I. S Balashov

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: i_balashov@oparina4.ru
Researcher of Biostatistics Laboratory 117997, Russia, Moscow, Ac. Oparina str. 4

A. S Gus

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: a_gus@oparina4.ru
MD, Head of Functional Diagnostics at the Department of Diagnostic Imaging 117997, Russia, Moscow, Ac. Oparina str. 4

V. A Bychenko

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: v_bychenko@oparina4.ru
M.D., Ph.D., Head of the Radiology Department 117997, Russia, Moscow, Ac. Oparina str. 4

R. B Matronitsky

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: r_matronitskiy@oparina4.ru
endoscopist doctor of the Surgery Department 117997, Russia, Moscow, Ac. Oparina str. 4

V. N Serov

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: v_serov@oparina4.ru
MD, Professor, Academician of the Russian Academy of Sciences 117997, Russia, Moscow, Ac. Oparina str. 4

References

  1. Адамян Л.В., Андреева Е.Н., Аполихина И.А., Беженарь В.Ф. и др. Эндометриоз: диагностика, лечение и реабилитация. Федеральные клинические рекомендации по ведению больных. М., 2013. 65 c
  2. Challenges in the development of novel therapeutic strategies for treatment of endometriosis / Vanhie A. [et al.]. Expert opinion on therapeutic targets. 2016; 20(5): 593-600. DOI: 10,1517 / 14728222.2016.1118461
  3. Борисова А.В. Ранняя диагностика наружного генитального эндометриоза и его рецидивов путем определения липидного профиля методом масс-спектрометрии: дис.. канд. мед. наук: 14.01.01. М., 2017. 192 с.
  4. Чернуха Г.Е., Ильина Л.М., Адамян Л.В., Павлович С.В. Глубокий инфильтративный эндометриоз: послеоперационные рецидивы и возможные пути их профилактики. Акушерство и гинекология. 2015; 8: 39-46
  5. Ata B, Mumusoglu S, Aslan K., Seyhan A., Kasapoglu I., Avci B., Urman B., Bozdag G, Uncu G. Which is worse? Comparison of ART outcome between women with primary or recurrent endometriomas. Hum Reprod. 2017; 32(7): 1427-31. DOI: 10,1093 / humrep / dex099
  6. Сонова М.М., Адамян Л.В., Жорданиа К.И., Паяниди Ю.Г. Эндометриоз и рак яичников. Есть ли взаимосвязь? Общие патогенетические черты рака яичников и эндометриоза. Онкогинекология. 2013; 4: 30-40.
  7. Kennedy S., Bergqvist A., Chapron C., et al. ESHRE guideline for the diagnosis and treatment ofendometriosis. Hum Reprod. 2005; 20: 2698-2704. PMID: 15980014 doi: 10.1093/humrep/dei135
  8. Evans M.B., Decherney A.H. Fertility and Endometriosis. Clin Obstet Gynecol. 2017; 60 (3): 497-502. doi: 10.3892/etm.2018.6307
  9. Signorile P.G., Baldi A. Looking for an effective and non-invasive diagnostic test for endometriosis: where are we? Ann Transl Med. 2018; 6(Suppl 2): 106. doi: 10.21037/atm.2018.11.46. PubMed PMID: 30740427; PubMed Central PMCID:PMC6330624.
  10. Bulun S.E. Endometriosis. N Engl J Med. 2009; 360: 268-79. doi: 10.1056/ NEJMra0804690
  11. Ballard K., Lowton K., Wright J.T. What>s the delay? A qualitative study of women>s experience of reaching a diagnosis of endometriosis. Fertil Steril. 2006; 86: 1296301. doi: 10.1016/j.fertnstert.2006.04.054
  12. D’Hooghe T.M., Mihalyi A.M., Sisma P., et al. Why we need a noninvasive diagnostic test for minimal to mild endometriosis with high sensitivity. Gynecol Obstet Invest 2006; 62:136-8. doi: 10.1159/000093120
  13. О D.F., Flores I., Waelkens E., et al. Noninvasive diagnosis of endometriosis: Review of current peripheral blood and endometrial biomarkers. Best Pract Res Clin Obstet Gynaecol 2018; 50: 72-83. doi: 10.1016/j.bpobgyn.2018.04.001
  14. Gupta D., Hull M.L., Fraser I., et al. Endometrial biomarkers for the non-invasive diagnosis of endometriosis. Cochrane Database Syst Rev 2016; 4: CD012165. doi: 10.1002/14651858.CD012165.
  15. Exacoustos C., Zupi E., Piccione E. Ultrasound Imaging for Ovarian and Deep Infiltrating Endometriosis. Semin Reprod Med. 2017; 35(1): 5-24. doi: 10.1055/ s-0036-1597127. Epub 2017 Jan 11. Review. PubMed PMID: 28076877.
  16. Reid S., Condous G. Update on the ultrasound diagnosis of deep pelvic endometriosis. Eur J Obstet Gynecol Reprod Biol. 2017; 209: 50-54. doi: 10.1016/j. ejogrb.2016.02.040. Epub 2016 Mar 8. Review. PubMed PMID: 27080442.
  17. van den Bosch T.,, van Schoubroeck D. Ultrasound diagnosis of endometriosis and adenomyosis: State of the art. Best Pract Res Clin Obstet Gynaecol. 2018 Aug; 51: 16-24. doi: 10.1016/j.bpobgyn.2018.01.013. Epub 2018 Feb 14. Review. PubMed PMID: 29506961.
  18. Guerriero S., Saba L., Pascual M.A., Ajossa S., Rodriguez I., Mais V., Alcazar J.L.Transvaginal ultrasound vs magnetic resonance imaging for diagnosing deep infiltrating endometriosis: systematic review and meta-analysis. Ultrasound Obstet Gynecol. 2018 May; 51(5): 586-595. doi: 10.1002/uog.18961. Review. PubMed PMID: 29154402.
  19. Bazot M, Darai E. Diagnosis of deep endometriosis: clinical examination, ultrasonography, magnetic resonance imaging, and other techniques. Fertil Steril. 2017; 108(6): 886-894. doi: 10.1016/j.fertnstert.2017.10.026. Review. PubMed PMID: 29202963.
  20. Guerriero S., Ajossa S., Minguez J.A., Jurado M., Mais V., Melis G.B, Alcazar J.L. Accuracy of transvaginal ultrasound for diagnosis of deep endometriosis in utero-sacral ligaments, rectovaginal septum, vagina and bladder: systematic review and meta-analysis. Ultrasound Obstet Gynecol. 2015; 46(5): 534-45. doi: 10.1002/ uog.15667. Review. PubMed PMID: 26250349.
  21. Guerriero S., Alcazar J.L., Pascual M.A., Ajossa S., Perniciano M., Piras A., Mais V., Piras B., Schirru F., Benedetto M.G., Saba L. Deep Infiltrating Endometriosis:Comparison Between 2-Dimensional Ultrasonography (US), 3-Dimensional US, and Magnetic Resonance Imaging. J Ultrasound Med. 2018; 37(6): 1511-1521. doi: 10.1002/jum.14496. Epub 2017 Nov 30. PubMed PMID: 29193230.
  22. Abd El-Kader A.I., Gonied A.S., Lotfy Mohamed M., Lotfy Mohamed S. Impact of Endometriosis-Related Adhesions on Quality of Life among Infertile Women. Int J Fertil Steril. 2019; 13(1): 72-76. doi: 10.22074/ijfs.2019.5572. Epub 2019 Jan PubMed PMID: 30644248; PubMed Central PMCID: PMC6334013.
  23. Tomiguchi J., Miyamoto H., Ozono K., Gushima R., Shono T., Naoe H., Tanaka M., Baba H., Katabuchi H., Sasaki Y. Preoperative Diagnosis of Intestinal Endometriosis by Magnifying Colonoscopy and Target Biopsy. Case Rep Gastroenterol. 2017; 11(2): 494-499. doi: 10.1159/000475751.
  24. van der Wat J, Kaplan M.D. Modified Virtual Colonoscopy in the Diagnosis and Quantification of Bowel and Disseminated Endometriosis. Surg Technol Int. 2015; 26:19-24. PubMed PMID: 26054986.
  25. Milone M, Mollo A., Musella M., Maietta P., Sosa Fernandez L.M., Shatalova O, Conforti A., Barone G., De Placido G., Milone F. Role of colonoscopy in the diagnostic work-up of bowel endometriosis. World J Gastroenterol. 2015; 21(16): 4997-5001. doi: 10.3748/wjg.v21. i16.4997. PubMed PMID: 25945014; PubMed Central PMCID: PMC4408473.
  26. Kavoussi S.K., Lim C.S., Skinner B.D., Lebovic D.I., As-Sanie S. New paradigms in the diagnosis and management of endometriosis. Curr Opin Obstet Gynecol. 2016; 28(4): 267-76. doi: 1.1097/GCO.0000000000000288. Review. PubMed PMID: 27306924.
  27. Liu X., Long Q., Guo S.W. Surgical History and the Risk of Endometriosis: A Hospital-Based Case-Control Study. Reprod Sci. 2016 Sep;23(9):1217-24. doi: 10.1177/1933719116632921. Epub 2016 Feb 25. PubMed PMID: 26919976.

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