Contrast-enhanced ultrasound in differential diagnosis of breast lesions


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Abstract

Aim. To determine the feasibility of contrast-enhanced ultrasound (CEUS) in the differential diagnosis of breast lesions. Materials and methods. This observational cohort study included results of CEUS performed in 145 women aged 17-74 (mean 45.8) years with benign and malignant nodular breast lesions. The patients were examined and treated at the V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology, and Perinatology of Minzdrav of Russia, Moscow, from December 2017 to December 2018. Results. The following eight parameters were significantly different in nodular breast lesions (p < 0.05): GOF, BI, AS, TTP, PI, DT / 2, DS, and AUC; 3parameters (GOF, DT/2, and DS) were significantly different in the peritumoral breast parenchyma. Conclusion. The analysis of the CEUS data identified several quantitative parameters both in the nodular breast lesions and in the peritumoral breast parenchyma that may be used for differential diagnosis.

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About the authors

A. N Sencha

V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology of Minzdrav of Russia

Email: a_sencha@oparina4.ru

Yu. V Bikeev

V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology of Minzdrav of Russia

Email: yu.bikeev@gmail.com

V. V Radionov

V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology of Minzdrav of Russia

L. B Shubin

Yaroslavl' State Medical University

E. A Sencha

Medical Diagnostic Center No. 9

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