Ultrasound diagnosis in the evaluation of parasternal lymph nodes in patients with breast canc er


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Objective. To enhance the effectiveness of diagnosing metastatic parasternal lymph nodes in patients with breast cancer (BC). Subjects and methods. The investigation enrolled 52 patients treated at the N.N. Blokhin National Medical Research Center of Oncology and diagnosed with BC. All patients underwent ultrasound examination (USE) of the breast and parasternal lymph nodes. Results. A total of 28 enlarged lymph nodes were detected. Enlarged parasternal lymph nodes were diagnosed in 19 (37%) patients; 7 (13.5%) patients had lymph nodes visualized in two or more intercostal spaces. There were 6 (21.4%) lymph nodes with signs of the specific lesion; 5 (9.6%) with metastatic parasternal lymph nodes; the stage of the disease was adjusted to higher one (IIIA) due to damage to the parasternal lymphatic collector. Analysis of estrogen and progesterone receptors (ER and PR) and HER2 showed that there was a basal-like, triple negative subtype of BC, ER-0, PR-0, HER2-0, Ki67> 80% in all cases of metastatic lesion. Conclusion. USE in evaluating the parasternal lymph nodes can be a useful tool for identifying metastatic lymph nodes

Full Text

Restricted Access

About the authors

V. M Snitkin

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

Email: snitkinvm@yandex.ru
post-graduate student of the Department of ultrasound diagnostics of the research Institute of clinical and experimental radiology

N. D Khakurinova

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

Email: nafset270l@mail.ru
post-graduate student of the Department of radiosurgery research Institute of clinical Oncology

V. N Sholokhov

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

Email: vnshell@mail.ru
Doctor of Medical Sciences, Professor, leading researcher of the Department of ultrasound diagnostics of the research Institute of clinical and experimental radiology

S. N Berdnikov

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

Email: berdnikov_sn@mail.ru
PhD, researcher of the Department of ultrasound diagnostics of the research Institute of clinical and experimental radiology

M. S Makhotina

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

Email: maria.mahotina@gmail.com
PhD, physician of the Department of ultrasound diagnostics of the research Institute of clinical and experimental radiology

R. K Valiev

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

Email: info@ronc.ru
PhD., head of the Department of radiosurgery of the research Institute of clinical Oncology. N. N. Trapeznikova

G. T Sinyukova

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

Email: profsinukova@mail.ru

A. I Gus

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: a_gus@oparina4.ru
MD, Head of Functional Diagnostics at the Department of Diagnostic Imaging

References

  1. Kim S.H. Breast Magnetic Resonance Imaging for Assessment of Internal Mammary Lymph Node Status in Breast Cancer. J Breast Cancer. 2016;19(2):191 8
  2. Kim E.J., Kim S.H., Kang B.J., Choi B.G., Song B.J., Choi J.J. Diagnostic value of breast MRI for predicting metastatic axillary lymph nodes in breast cancer patients: diffusion-weighted MRI and conventional MRI. Magn Reson Imaging. 2014;32:1230-6.
  3. He N., Xie C., Wei W., Pan C., Wang W., Lv N., et al. A new, preoperative, MRI-based scoring system for diagnosing malignant axillary lymph nodes in women evaluated for breast cancer. Eur J. Radiol. 2012;81:2602-12.
  4. Fornasa F., Nesoti M.V., Bovo C., Bonavina M.G. Diffusion-weighted magnetic resonance imaging in the characterization of axillary lymph nodes in patients with breast cancer. J. Magn Reson Imaging. 2012;36:858-64.
  5. Ozdemir H., Atilla S., Ilgit E. T., I§ik S. Parasternal sonography of the internal mammary lymphatics in breast cancer: CT correlation. Eur J. Radiol. 1995 Jan;19(2):114-7
  6. Scatarige JC, Hamper UM, Sheth S., Allen HA 3rd. Parasternal sonography of the internal mammary vessels: technique, normal anatomy, and lymphadenopathy. Radiology. 1989 Aug;172(2):453-7.
  7. Sobin L.H., Gospodarowicz M.K., Witte kind Ch., eds. TNM Classification of Malignant Tumours, 7th ed. N.Y.: Wiley-Blackwell; 2009. 310 p.
  8. Коваленко В. Л., Мусафиров М. Ф., Бурлаченко Р. В. Опыт видеоторакоскопической парастернальной лимфодиссекции при раке молочной железы. Дальневосточный медицинский журал. 2014;2:28-30.
  9. Уйманов В.А., Нечушкин М.И., Триголосов А.В., Петровский А.В., Вишневская Я.В., Зайцева А.А. Хирургические методики морфологической оценки состояния парастернального лимфатического коллектора в составе органосохраняющего лечения больных раком молочной железы. Вестник РОНЦ им. Н. Н. Блохина РАМН. 2012. 23(3):29-34.
  10. Shozushima M., Suzuki M., Nakasima T. et al. Ultrasound diagnosis of lymph node metastasis in head and neck cancer // Dentomaxillofac. Radiol. 1990. 19(4):165-170.
  11. Vassallo P., Wernecke K., Roos N., Peters P.E. Differentiation of benign from malignant superfi cial lymphadenopathy: the role of highresolution US // Radiology. 1992. 183(1):215-220.
  12. Аллахвердян Г.С., Чекалова М.А. Возможности ультразвукового исследования в диагностике патологии поверхностных лимфатических узлов. Ультразвуковая и функциональная диагностика. 2011; 1:77-84.

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2019 Bionika Media

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies