Ultrasound diagnosis in the evaluation of parasternal lymph nodes in patients with breast canc er


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Abstract

Objective. To enhance the effectiveness of diagnosing metastatic parasternal lymph nodes in patients with breast cancer (BC). Subjects and methods. The investigation enrolled 52 patients treated at the N.N. Blokhin National Medical Research Center of Oncology and diagnosed with BC. All patients underwent ultrasound examination (USE) of the breast and parasternal lymph nodes. Results. A total of 28 enlarged lymph nodes were detected. Enlarged parasternal lymph nodes were diagnosed in 19 (37%) patients; 7 (13.5%) patients had lymph nodes visualized in two or more intercostal spaces. There were 6 (21.4%) lymph nodes with signs of the specific lesion; 5 (9.6%) with metastatic parasternal lymph nodes; the stage of the disease was adjusted to higher one (IIIA) due to damage to the parasternal lymphatic collector. Analysis of estrogen and progesterone receptors (ER and PR) and HER2 showed that there was a basal-like, triple negative subtype of BC, ER-0, PR-0, HER2-0, Ki67> 80% in all cases of metastatic lesion. Conclusion. USE in evaluating the parasternal lymph nodes can be a useful tool for identifying metastatic lymph nodes

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About the authors

V. M Snitkin

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

Email: snitkinvm@yandex.ru
post-graduate student of the Department of ultrasound diagnostics of the research Institute of clinical and experimental radiology

N. D Khakurinova

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

Email: nafset270l@mail.ru
post-graduate student of the Department of radiosurgery research Institute of clinical Oncology

V. N Sholokhov

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

Email: vnshell@mail.ru
Doctor of Medical Sciences, Professor, leading researcher of the Department of ultrasound diagnostics of the research Institute of clinical and experimental radiology

S. N Berdnikov

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

Email: berdnikov_sn@mail.ru
PhD, researcher of the Department of ultrasound diagnostics of the research Institute of clinical and experimental radiology

M. S Makhotina

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

Email: maria.mahotina@gmail.com
PhD, physician of the Department of ultrasound diagnostics of the research Institute of clinical and experimental radiology

R. K Valiev

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

Email: info@ronc.ru
PhD., head of the Department of radiosurgery of the research Institute of clinical Oncology. N. N. Trapeznikova

G. T Sinyukova

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

Email: profsinukova@mail.ru

A. I Gus

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: a_gus@oparina4.ru
MD, Head of Functional Diagnostics at the Department of Diagnostic Imaging

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