Clinical and epidemiological aspects of corpus uteri cancer in the context of prevention of recurrent endometrial hyperplasia


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Abstract

Objective. To analyze trends in the incidence of corpus uteri cancer (CUC) in the Omsk Region in 2002-2018 to prioritize cancer prevention in patients with endometrial hyperplasia (EH). Material and methods. A continuous descriptive observational retrospective epidemiological study of CUC incidence rates was conducted using official statistics. Results. There was a moderate tendency for higher CUC incidence rates in the region (Growth rate (Gr) = +1.8%; p < 0.001) and in the Russian Federation (Gr = +1.7%; p <0.001). The highest proportion was 32.3% of women aged 60-69 years. There was a moderate tendency for increased CUC incidence rates among 30 to 39 year olds and a marked tendency for higher ones in women aged 35-39 years (Gr = +5.6%; p <0.05). A rationale was provided for an integrated approach to managing patients with EH in the context of prevention of the recurrent disease. Conclusion. It was established that the Omsk Region showed a rise in CUC incidence and a tendency for patients with th is disease to become younger. One of the measures to reduce the risk of HE recurrence and progression is the need for a preventive therapy cycle, by taking into account endometrial morphological control.

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About the authors

Tatiana V. Klinyshkova

Omsk State Medical University Ministry of Health of Russia

Email: klin_tatyana@mail.ru
MD, Full Professor, Professor of the Graduate Education Department of obstetrics and gynecology 644043 Russia, Omsk, Lenin Str., 12

Denis V. Turchaninov

Omsk State Medical University Ministry of Health of Russia

Email: omskgsen@yandex.ru
MD, Full Professor, Head of the Department of Hygiene and Nutrition 644043 Russia, Omsk, Lenin Str., 12

Natalia B. Frolova

Railway Clinical Hospital at the Omsk Passenger Station OAO "RZhD"

Email: nbfrolova@yandex.ru
PhD, Head of gynecological Department 644005 Russia, Omsk, Karbysheva str., 41

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