Current views on microbiota in gynecology


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Abstract

The paper reviews publications on the microbiota state in endometriosis, various endometrial abnormalities (endometrial polyps, endometrial hyperplasia, chronic endometritis), and endometrial cancer, as well as in infertility. The investigators identified certain microorganisms that can be potentially considered as predictors for the effectiveness of assisted reproductive technology (ART) programs. An analysis of the literature proves the relationship of microbiome disorders to the development of benign and malignant diseases. The investigation results raise questions regarding the molecular mechanisms of tissue and cellular homeostatic disorders between the microbiota and the human body in various pathological processes. These support the expediency of conducting investigations in this area.

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About the authors

Gyuzyal I. Tabeeva

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: doctor.gtab@gmail.com
Ph. D., senior researcher of the Department of gynecological endocrinology

Madina R. Dumanovskaya

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Ph. D., researcher of the Department of gynecological endocrinology

Galina E. Chernukha

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

MD, Professor, head of the Department of gynecological endocrinology

Tatyana V. Priputnevich

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

doctor of medical Sciences, head of Department of Microbiology, clinical pharmacology and epidemiology

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