Prevalence of cervical cancer in the Far Eastern Federal District and ways to improve early detection of the disease

Aim. To investigate the prevalence, mortality, and detection rate of cervical cancer in the Far Eastern Federal District for the development and implementation of a cervical cancer screening program aimed to reduce mortality in the female population. Materials and methods. The study used statistical and analytical methods, including a retrospective analysis of official statistical indicators for cervical cancer in eight federal districts of the Russian Federation and 11 subjects of the Far Eastern Federal District, with a subsequent mathematical interpretation of the data. Mean values were calculated according to the generally accepted statistical methods. Results. In the Far Eastern Federal District, incidence rates of cervical cancer for the years 2014-2017 ranged from 17.33 to 21.36per 100,000 of female population, which were greater than that in the Russian Federation (from 14.47to 15.76, respectively). In 2018, the Far East Federal District had the highest prevalence of cervical cancer in the Russian Federation (152.3 vs.123.7 per 100,000 of female population). Regional problems include low cervical screening coverage for the female population aged 21-69 at 50.53% (CI 10.0-78.7%) (target> 70%) and active detection of cervical cancer at 48.58% ( CI 33.51-66.7%) (target indicator for stage I - II cervical cancer identifiable by visual inspection> 70%). Conclusion. The Far Eastern Federal District has the highest prevalence of cervical cancer, which requires the active implementation of an organized cervical screening program based on human papillomavirus and cytology co-testing and accessible to people living in remote rural areas of the region.

cervical cancer, incidence, mortality, diagnosis, screening