THE POSITIVE EFFECT OF PREGNANCY ON OVARIAN ENDOMETRIOSIS: REALITY OR FICTION?


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Abstract

It is generally believed that pregnancy positively affects endometriosis mainly due to suppression of ovulation and bleeding resulting from endometriotic lesions and various alterations associated with pregnancy. Pregnancy is usually recommended as a possible factor to reduce the progression of endometriosis for women with this condition. Nonetheless, endometriosis can develop differently and that there is no evidence that pregnancy can generally reduce the size and number of endometriotic lesions. Expansion of and structural changes in the lesions during pregnancy may be accompanied by decidualization. The results of studying the effect of pregnancy on endometriosis are controversial, whereas pregnancy in women with endometriosis is not always associated with improved symptoms. This paper highlights the progression of endometriosis during pregnancy and subsequent acute complications that require surgery in some cases. Therefore, women with endometriosis who want to get pregnant should not be convinced that pregnancy may be a possible strategy for managing symptoms and reducing disease progression. Conclusion. The results of studying the effect of pregnancy on endometriosis are controversial, whereas pregnancy in women with endometriosis is not always associated with improved symptoms.

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About the authors

Svetlana O. DUBROVINA

Rostov State Medical University, Ministry of Health of Russia

Email: s.dubrovina@gmail.com
MD, professor, the main scientific researcher of Scientific Research Institute of Obstetric and Pediatric Rostov-on-Don, Russia

Yuliya D. BERLIM

Rostov State Medical University, Ministry of Health of Russia

Email: juliaberlim@yandex.ru
PhD, MD, the Head of Department of the out-patients' clinic Rostov-on-Don, Russia

Vitaliy S. GIMBUT

Rostov State Medical University, Ministry of Health of Russia

Email: vgimbut@gmail.com
PhD, MD, senior scientific researcher of Scientific Research Institute of Obstetrics and Pediatrics Rostov-on-Don, Russia

Marina A. VOVKOCHINA

Rostov State Medical University, Ministry of Health of Russia

Email: Jordan-85@inbox.ru
gynecologist obstetrician of Scientific Research Institute of Obstetric and Pediatric Rostov-on-Don, Russia

Olga V. VORONOVA

RZhD-Medicine Clinical Hospital

Email: 9043401873@mail.ru
the leader of Department of clinical pathomorphology and cytology Rostov-on-Don, Russia

Anna D. ALEKSANDRINA

Rostov State Medical University, Ministry of Health of Russia

Email: anna221215@inbox.ru
gynecologist obstetrician Rostov-on-Don, Russia

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