Comorbid conditions in genital prolapse


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Abstract

Subjects and methods. This paper evaluates extragenital disease and previous surgical interventions in women operated on. A total of 718 patients with POP- Q grade II-IV were operated on; 62 patients underwent bone mineral density (BMD) estimation. Statistical processing was performed using SPSS17 Statistics 17.0 and StatSoft STATISTICA 10.0. Results. The anamnesis contained predominantly cardiovascular disorders: grade I hypertensive disease (HD) in 30 (4.2%) women, grade II HD in 194 (27.0%) patients, grade IIIHD in 40 (5.6%), lower extremity varices in 40 (8.4%), and diabetes mellitus (DM) in 38 (5.3%). An ROC analysis could provide evidence for the hypothesis that HD had an impact on the increase in the incidence of genital prolapse (AUC = 0.643±0.03; p = 0.012). Conclusion. The age-related combination of HD, DM, lower BMD, and POP-Q grade II-IV is an urgent problem. Additional studies of this group of diseases are required to determine the factors that influence the deterioration of the course of these interrelated conditions, to define criteria of inclusion into risk groups, and to improve methods for diagnosis and treatment of this comorbidity.

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About the authors

Il’nur I. Musin

Bashkir State Medical University, Ministry of Health of the Russian Federation

Email: ilnur-musin@yandex.ru
Cand. Med. Sci., Associate Professor of the Department of Obstetrics and Gynecology with course ISPE

Alfiya G. Yashchuk

Bashkir State Medical University, Ministry of Health of the Russian Federation

Email: alflya_galimovna@mail.ru
Doc. Med. Sci., Professor, Head of the Department of Obstetrics and Gynecology with course ISPE

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