Vaccination during pregnancy: present and future


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Abstract

Vaccination during pregnancy, which is finding increasing use worldwide, is one of the most effective and promising strategies for preventing morbidity and mortality from infectious diseases among pregnant women and newborn babies. Vaccination for pregnant women has been shown to be highly effective and safe in a number of important infections, such as influenza, pertussis, and tetanus. As there is more evidence that vaccination during pregnancy against the novel coronavirus infection is effective and safe, an increasing number of countries include it in priority vaccination programs. In recent years, progress has been made to design new vaccines against Group B streptococcus, respiratory syncytial virus, and cytomegalovirus, which are designed mainly for pregnant women. According to many studies, an obstetrician/gynecologist’s vaccination recommendation with sufficient information on the need and safety of vaccination for a woman and a newborn baby is a key factor for a pregnant woman’s decision to get vaccinated. Conclusion: This review analyzes the literature on the main aspects of vaccination during pregnancy: the efficacy and safety of currently recommended vaccines and the factors influencing the attitude of pregnant women to vaccination. It discusses the issues of pregnant women’s vaccination against the novel coronavirus infection and the promising areas and developments in vaccination during pregnancy.

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About the authors

Elena V. Shipitsyna

D.O. Ott Research Institute of Obstetrics, Gynecology, and Reproductology

Email: shipitsyna@inbox.ru
Dr. Bio. Sci., Leading Researcher of the International Department

Natalia Yu. Shirshova

City Polyclinic No. 32, Saint Petersburg

Email: p32@zdrav.spb.ru
PhD, Head Physician

Igor Yu. Kogan

D.O. Ott Research Institute of Obstetrics, Gynecology, and Reproductology

Email: ovrt@ott.ru
Corresponding Member of RAS, Dr. Med. Sci., Professor, Director

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