Analysis of correlations between the results of diagnostic studies of diseases of the cervix uteri
- Authors: Kazakova A.V.1, Lineva O.I.1, Kozupitsa G.S.2, Chechko S.M.3, Rustianova D.R.1
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Affiliations:
- Samara State Medical University, Ministry of Health of the Russian Federation
- Samara State University of Railway Transport
- N.A. Semashko Samara City Hospital No. 2
- Issue: No 12 (2021)
- Pages: 153-158
- Section: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/249436
- DOI: https://doi.org/10.18565/aig.2021.12.153-158
- ID: 249436
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Abstract
Objective: To identify relationships between age, cytological and histological findings, colposcopic patterns, and the presence of high-risk human papillomavirus (HPV) in patients with cervical disease. Materials and methods: The investigation enrolled 50 women aged 23 to 65 years. All the women underwent traditional and liquid-based cervical cytology. Their epithelial cells were scraped and examined for HPV by realtime PCR; their biopsy specimens underwent colposcopy and histology. Results: There was a high relationship between the histological f indings of CIN 3 and CIN 2 and the presence of HPV. The highest likelihood of being diagnosed with CIN 3 was found in HPV types 16 and 18 (52%). There were statistically significant positive correlations between colposcopic diagnosis and histological findings, as well as moderate negative correlations between colposcopic diagnosis and the type of transformation zone and weak negative ones between colposcopic diagnosis and age. Conclusion: There is a clear relationship between the histological findings of CIN 3 and the presence of HPV types 16 and 18. Colposcopic diagnosis of cervical diseases is most informative under 40 years of age and in the presence of Type I transformation zone.
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About the authors
Anna V. Kazakova
Samara State Medical University, Ministry of Health of the Russian Federation
Email: amigo14021980@yandex.ru
MD, Dr. Sci. (Med), Head of the Department of Obstetrics and Gynecology No. 2
Olga I. Lineva
Samara State Medical University, Ministry of Health of the Russian FederationMD, Dr. Sci. (Med), Professor of the Department of Obstetrics and Gynecology № 2
Gennadiy S. Kozupitsa
Samara State University of Railway TransportDr. Sci. (Bio), Professor of the Department of Physical Education and Sports
Svetlana M. Chechko
N.A. Semashko Samara City Hospital No. 2MD, obstetrician-gynecologist, Department of Operative Gynecology
Daria R. Rustianova
Samara State Medical University, Ministry of Health of the Russian Federation
Email: angel04121993@mail.ru
MD, Assistant of the Department of Obstetrics and Gynecology No. 2
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