Main criteria and risk factors for the development of recurrent endometriosis


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Abstract

Objective: To analyze the data available in the current literature on the recurrence of different forms of endometriosis and to identify the main criteria and risk factors for the development of a relapse of the disease. The review article includes the data published by foreign and Russian authors in the Pubmed, UpToDate, and eLibrary databases on the keywords "endometriosis", " deep infiltrating endometriosis", and "recurrent endometriosis". Endometriosis is observed in 10% of reproductive-aged women and ranks third among gynecological diseases. The literature review focuses on risk factors for recurrent endometriosis. The term “recurrent endometriosis” is non-uniform and ambiguous; different studies describe various parameters of recurrent disease. This concept is used in different sources of literature in different ways: as recurrent pain, as the detection of new lesions by pelvic ultrasound or MRI, as a repeated increase in CA-125 levels, or as a surgical finding of new endometrioid implants during surgery unassociated with endometriosis. Conclusion: At the moment, there are no unified clinical and molecular criteria for recurrent endometriosis. The lack of understanding of risk factors for recurrent endometriosis cannot build a unified strategy for early diagnosis, timely therapy and surgical treatment

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About the authors

Daria N. Senina

I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia; Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: seninadashal995@gmail.com
PhD student, Surgical Department

Vladimir D. Chuprynin

Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: v_chuprynin@oparina4.ru
PhD, Head of the Surgical Department

Natalya A. Buralkina

Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: ralkina@yandex.ru
Dr. Med. Sci., Senior Researcher at Surgical Department

Vyacheslav V. Chursin

Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: v_chursin@oparina4.ru
surgeon at the Department of General Surgery

Tatyana Yu. Smolnova

Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: smoltat@list.ru
Dr. Med. Sci., Senior Reseacher at the Surgery Department

Liana Yu. Davidyan

Ulyanovsk State University

Email: dliana2009@mail.ru
Dr. Med. Sci., Professor of the Faculty of postgraduate medical and pharmaceutical education

Azizbek S. Abosov

Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: abosovazizbekll@gmail.com
resident

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