The role of high-intensity focused ultrasound treatment in patients with uterine myoma

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Abstract

Uterine myoma is the most common benign tumor in gynecological practice and the leading cause of hysterectomy. This pathology has clinical manifestations in every three female patients, decreases quality of life and level of fertility in reproductive-aged women, and also substantially affects the human potential of any country. Uterine fibroids can be now treated with various medical, surgical, interventional, and ablative methods that differ in the nature of their impact, in the criteria for selecting female patients, in the required level of technical equipment, and in economic characteristics. In connection with to the active introduction of modern minimally traumatic local treatments into wide practice, high-intensity focused ultrasound therapy, a non-invasive thermal ablation technique for solid neoplasms at various sites, is of particular interest to patients with uterine myoma. The literature review presents the possibilities of using high-intensity focused ultrasound therapy in patients with uterine myoma; highlights the advantages and disadvantages of this type of local thermal effect in the treatment of a benign uterine tumor; determines indications for and contraindications to highintensity focused ultrasound therapy; describes the main complications of ultrasound ablation and ways for their prevention; identifies criteria for the efficiency of treatment, as viewed from both the general somatic characteristics of a woman and the biological characteristics of a myomatous node and the parameters of the procedure; and demonstrates the clinical results of local treatment (the time course of changes in tumor sizes, pain syndrome level, menorrhagia volume) and its impact on female reproductive abilities. Conclusion: The present study has shown that high-intensity focused ultrasound therapy can be considered as an affordable, effective, relatively safe method to treat patients with uterine myoma.

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About the authors

Liudmila I. Moskvicheva

P.A. Herzen Moscow Oncology Research Institute, Branch, National Medical Radiology Research Center, Ministry of Health of the Russian Federation

Email: ludamedl6@mail.ru
oncologist at the Ultrasound Department

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