Relationship between hypothyroidism and hyperprolactinemia


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Abstract

Thyroid diseases and hyperprolactinemia are now one of the most urgent problems that are of great medical and social significance. The literature describes concurrent primary hypothyroidism and hyperprolactinemia as Van Wyk-Ross-Hennes syndrome. The authors have analyzed the data available in the literature on hypothyroidism and hyperprolactinemia, in particular, their relationship to each other. The paper provides evidence supporting the relationship between hypothyroidism and elevated prolactin levels. Attention is focused on the presence of a causal relationship between hypothyroidism and the development of hyperprolactinemia. The paper includes publications available in the PubMed, Web of Science, Google Scholar, and eLIBRARY.RU databases by keywords. Conclusion: This literature review indicates a close relationship between the levels of thyroid hormones and prolactin. However, a number of authors point to that hypothyroidism triggers higher prolactin levels, while other authors believe that hyperprolactinemia implies an increase in thyroid hormone levels. The above data indicate a long-term experience in studying this relationship and the lack of a consensus of opinion, which enables us to conclude that this issue is still open

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About the authors

Lyailya Zh. Shormanova

Astana Medical University

Email: lyailyazhansultanovna@gmail.com
Doctoral Candidate, PhD, First-Year

Zarema T. Gabdiliashimova

Astana Medical University

MD, Associate Professor, Obstetrics and Gynecology Department One

Zaituna G. Khamidullina

Astana Medical University

Cand. Med. Sci., PhD, Head, Obstetrics and Gynecology Department One

Gainyl U. Akhmediyanova

Astana Medical University

Cand. Med. Sci., Professor, Obstetrics and Gynecology Department One

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