The fetal myocardial performance index: physiology and clinical significance


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Abstract

Functional assessment of the fetal cardiovascular system is an important method for monitoring its condition in health and disease. The myocardial performance index (MPI) based on the principles of heart cycle phase analysis is a new information indicator for the systolic and diastolic functions of the fetal heart. Since the introduction of MPI, its correct definition makes significant demands for a procedure to record cardiac time intervals and their reproducibility and to develop standard indicators. Application of MPI shows early and significant changes in fetal cardiac function in diseases, such as fetal growth retardation, maternal diabetes, severe heart defects, and fetofetal transfusion in monochorionic twins. Conclusion. Further studies of the sensitivity of MPI to cardiac loading conditions, its correlation with the results of tissue Doppler imaging and automated calculation will be able to use this index as an effective diagnostic tool in studying the fetal cardiovascular system in different types of obstetric pathology.

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About the authors

Pavel B. Tsyvian

Ural Research Institute of Maternal and Infant Care, Ministry of Health of Russia; Ural State Medical University, Ministry of Health of Russia,

Email: pavel.tsyvian@gmail.com
D.Sc., Professor, Senior researcher

Galina B. Malgina

Ural Research Institute of Maternal and Infant Care, Ministry of Health of Russia

Email: galinamalgina@mail.ru
D.Sc., Professor

Vladimir L. Kodkin

South Ural State University (National Research University)

Email: kodkinvl@susu.ru
D.Sc., Professor of Automated Electromotor Department

Natalia V. Kosovtsova

Ural Research Institute of Maternal and Infant Care, Ministry of Health of Russia

Email: kosovcovan@mail.ru
D.Sc., Head of Ultrasound Department

Tatyana V. Markova

Ural Research Institute of Maternal and Infant Care, Ministry of Health of Russia

Email: ta.ma.vl@mail.ru
M.D., Ph.D., Senior researcher

Olga A. Kraeva

Ural Research Institute of Maternal and Infant Care, Ministry of Health of Russia

Email: olalkra@yandex.ru
M.D., Ph.D., Senior researcher

Darya V. Mangalieva

Institute of Immunology and Physiology, Ural Branch, Russian Academy of Sciences

Email: alpendwarf@gmail.com
Junior researcher

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