Ovarian malignancy risk stratification. The integration of MRI into O-RADS


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Abstract

This review analyzes the current literature data on the radiodiagnosis of ovarian masses (OM), the problems of ovarian cancer screening, and modern classification methods in terms of the main characteristics and risks of OM malignancy. Ultrasound (US) is the first step in diagnostic imaging today. Many different systems have been developed to assess OM characteristics based on ultrasound indicators. One of the most promising current systems is the standardized scale to assess US results - Ovarian-Adnexal Reporting and Data System (O-RADS) that aims to improve interdisciplinary interactions between specialists and to increase diagnostic accuracy. Based on the existing O-RADS, an algorithm was presented in 2020 to assess the results and to stratify the risks of OM malignancy detected by Ovarian-Adnexal Reporting and Data System Magnetic Resonance Imaging (O-RADS MRI). This algorithm makes it possible to stratify the risk of OM malignancy, by evaluating the MRI pattern based on five formulated categories. Conclusion. According to the conducted studies, including external validation ones, O-RADS MRI demonstrates not only the accuracy of the scoring system and high efficiency, but also ease of use, which makes it possible to recommend the O-RADS MRI scale as a routine system for assessing MR images to differentiate and stratify the risks of OM malignancy in case of the uncertain degree of the latter, as evidenced by US.

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About the authors

Alina E. Solopova

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation

Email: a_solopova@oparina4.ru
MD, PhD, Associate Professor, Leading Researcher, Department of Radiology

Anastasiya N. Dudina

I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of the Russian Federation

Email: dudina97@mail.ru
6th year student, Institute of Children’s Health

Vladimir G. Bychenko

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation

Email: v_bychenko@oparina4.ru
MD, PhD, Head of the Department of Radiology

Natalia A. Rubtsova

RA. Herzen Moscow Oncology Research Institute, Branch, National Medical Radiology Research Center, Ministry of Health of the Russian Federation

Email: rnal7@yandex.ru
MD, PhD, Professor, Head of the Department of Radiology

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