Possibilities of ultrasonic shear wave elastography in the diagnosis of cervical cancer (first experience)
- Authors: Zykin B.I.1, Ogryzkova V.L.2, Ionova E.A.1
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Affiliations:
- I.I. Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency
- National Center for Oncology of Reproductive Organs, National Medical Research Radiological Center, Ministry of Health of Russia
- Issue: No 10 (2020)
- Pages: 113-117
- Section: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/329546
- DOI: https://doi.org/10.18565/aig.2020.10.113-117
- ID: 329546
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Abstract
Objective. To determine the diagnostic value of two-dimensional shear wave elastography in patients with cervical cancer. Materials and methods. Two-dimensional shear wave elastography was performed in the control group (in 20 women) and in 18 patients with confirmed cervical cancer. The study was performed using the Aixplorer ultrasound system (SSI, France). Results. There was a statistically significant (p<0.001) increase in the stiffness (Me=66.6 kPa (51; 88.7)) of cervical tissues affected by cancer, compared to the control group (Me=21.1 kPa (20; 23.5). ROC analysis showed that when using a 32 kPa cut-off value, the sensitivity, specificity, and prognostic value of the positive and negative results were 96%, 89%, 86%, and 95%, respectively. AUROC for this threshold reaches 0.97. Conclusion. Two-dimensional share wave elastography may be a new objective method for diagnosing cervical cancer.
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About the authors
Boris I. Zykin
I.I. Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency
Email: b.zykin@yandex.ru
MD, professor of Department of Diagnostic radiology
Vera L. Ogryzkova
National Center for Oncology of Reproductive Organs, National Medical Research Radiological Center, Ministry of Health of Russia
Email: verogr@yandex.ru
Ph.D., Leading Researcher
Elena A. Ionova
I.I. Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency
Email: ionela60@mail.ru
MD, Head of the Department of Diagnostic radiology
References
- Статистические данные и рак шейки матки. Available at: https://www. oncoforum.ru/o-rake/statistika-raka/rak-sheyki-matki-statistika-i-prognozy-vyzhivaemosti.html [Statistics and cervical cancer. (in Russian)].
- Зыкин Б.И., Постнова Н.А., Медведев В.Е. Эластография: анатомия метода. Променева дiагностика, променева тератя. 2012; 2-3: 107-13. [Zykin B.I., Postnova N.A., Medvedev V.E. Elastography: anatomy of the method. Promeneva diagnostics, promeneva therapy/Diagnostic radiology and radiotherapy. 2012; 2-3: 107-13. (in Russian)].
- Головко Т.С., Бакай О.А. Возможности эластографии в диагностике новообразований шейки матки. Здоровье женщины. 2014; 8: 112-7. [Golovko T.S., Bakay O.A. Possibilities of elastography in the diagnosis of cervical neoplasms. Women's health. 2014; 8 (94): 112-7. (in Russian)].
- Lu R., Xiao Y., Liu M., Shi D. Ultrasound elastography in the Ddfferential diagnosis of benign and malignant cervical lesions. J. Ultrasound Med. 2014; 33(4): 667-71. https://dx.doi.org/10.7863/ultra.33.4.667.
- Su Y., Du L., Wu Y., Zhang J., Zhang X., Jia X. et al. Evaluation of cervical cancer detection with acoustic radiation force impulse ultrasound imaging. Exp. Ther. Med. 2013; 5(6): 1715-9. https://dx.doi.org/10.3892/etm.2013.1057.
- Liu C., Li T., Hu Z., Li Y., Cheng X., Zhu Y, Lu M. Transvaginal real-time shear wave elastography in the diagnosis of cervical disease. J. Ultrasound Med. 2019; 38(12): 3173-81. https://dx.doi.org/10.1002/jum.15018.
- Dodampahala S.H., Jayakody S.N., Gunathilake W.C.C., Rahubaddha A.N., Dodampahala S.K. Transvaginal color Doppler in the assessment of cervical carcinoma and pre-cancer: evidence from a case control study using colour Doppler ultrasonography pulsatility index of uterine vasculature. Advanc. Reprod. Sci. 2016; 4: 93-9.
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