Androgen priming in a poor ovarian stimulation response
- Authors: Pshenisnova I.V.1, Yakovlev P.P.2
-
Affiliations:
- “MD Medical Yaroslavl”
- Centre for Reproductive Medicine, Co. Ltd. “Next Generation Clinic”
- Issue: No 8 (2023)
- Pages: 22-29
- Section: Reviews
- URL: https://journals.eco-vector.com/0300-9092/article/view/585239
- DOI: https://doi.org/10.18565/aig.2023.109
- ID: 585239
Cite item
Abstract
reproductive medicine. It is supposed that the use of dehydroepiandrosterone and testosterone before therapy in poor female responders can improve the outcomes of ART programs due to a better OS response. At the same time, there are conflicting data on the positive effect of androgen priming on OS indicators and the clinical outcomes of in vitro fertilization (IVF). This review considers the main issues regarding the efficiency and safety of adjuvant pretreatment androgen therapy (regimens, dosages, and duration) on the effectiveness of ART cycles in poor female OS responders.
Conclusion: There is a need for further relevant randomized clinical trials to confirm the benefits and safety of androgen therapy before OS in poor female OS responders in the IVF programs.
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About the authors
Irina V. Pshenisnova
“MD Medical Yaroslavl”
Author for correspondence.
Email: beslema@mail.ru
Obstetrician-Gynecologist
Russian Federation, YaroslavlPavel P. Yakovlev
Centre for Reproductive Medicine, Co. Ltd. “Next Generation Clinic”
Email: iakovlevpp@gmail.com
ORCID iD: 0000-0003-1443-9623
Obstetrician-Gynecologist
Russian Federation, MoscowReferences
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