Application of Alive Collagen supplement in genitourinary menopausal syndrome

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Abstract

Objective: To evaluate the efficacy and safety of Alive Collagen in postmenopausal women with genitourinary menopausal syndrome (GMS).

Materials and methods: This was a single-center, uncontrolled before-after study. Twenty-five women aged 50–68 years (mean age is 59.44±5.39 years) diagnosed with postmenopausal atrophic vaginitis were examined at the Family Clinic from April to June 2023. The efficacy of taking Alive Collagen at a dosage of 15 g/day for 12 weeks was evaluated. The analysis was carried out using a questionnaire with calculation of the Female Sexual Function Index (FSFI) and visual analog scale developed by R. Nappi.

Results: The postmenopausal period lasted 7±2.40 years, the duration of GMS symptoms ranged from 2 to 10 years (mean period is 5.44±2.63 years). In 12 weeks after taking Alive Collagen, the women noticed a decrease in the symptoms of GMS, namely, itching, burning, and vaginal dryness; a decrease in the severity of dyspareunia was also revealed. FSFI increased from 15.36±4.33 before therapy to 21.58±3.94 after collagen supplementation for 12 weeks. No adverse side effects were detected.

Conclusion: The patients suffering from various symptoms of GMS and having contraindications to menopausal hormone therapy can have a possible alternative to improve their quality of life by taking Alive Collagen supplement at a dose of 15 g/day 30 minutes before meals for 12 weeks.

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About the authors

Kamil R. Bakhtiyarov

I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)

Author for correspondence.
Email: doctorbah@mail.ru
ORCID iD: 0000-0001-7114-4050

Dr. Med. Sci., Professor, Sechenov First Moscow State Medical University

Russian Federation, 119991, Moscow, Trubetskaya str., 8-2

Polina I. Kuzmina

I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)

Email: kuzmina_p_i@student.sechenov.ru
ORCID iD: 0009-0004-0098-1774

Student of the Institute of Clinical Medicine named after N.V. Sklifosovsky

Russian Federation, 119991, Moscow, Trubetskaya str., 8-2

Anna V. Cherkashina

I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)

Email: cherkashina_a_v@student.sechenov.ru
ORCID iD: 0000-0002-3840-1948

Student of the Institute of Clinical Medicine named after N.V. Sklifosovsky

Russian Federation, 119991, Moscow, Trubetskaya str., 8-2

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