Сlinical characteristics of Syrian women with uterine leiomyoma

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Abstract

Objective: To analyze the clinical characteristics, risk factors, and impact on lifestyle of women with uterine leiomyomas (ULs) and compare these findings with a control group of healthy women.

Materials and methods: Conducted from June 2023 to August 2024, the study included 1,000 Syrian women (500 patients with ULs and 500 controls) aged 22–83 from various cities. A questionnaire formed of 65 questions containing information about the clinical characteristics and risk factors for the development of uterine leiomyomas was used. Data was analyzed using Statistical Packages for Software Sciences (SPSS) version 30.

Results: Revealed significant differences between patients and controls in age at first menstruation (p = 0.046), length of the menstrual cycle (p = 0.016), duration of the menstrual bleeding (p = 0.043), age at menopause (p < 0.001), time elapsed since the last birth (p < 0.001), and endometrial ablation (p = 0.039). Regarding the characteristics of the Fibrous nodes, it indicated that submucosal fibroids were in only 6/500 (1.2%) women, while pedunculated was in 22/500 (4.4%) women, subserosal was in 227/500 (45.4%), and intramural was in 228/500 (45.6%).

Conclusion: This study demonstrated which clinical characteristics and risk factors for uterine leiomyomas were statistically significant in Syrian women. This may help determine the best techniques to diagnose and treat them well in order to prevent complications and reduce their impact on health-related quality of life.

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About the authors

Ola M. Alali

Belgorod State National Research University

Author for correspondence.
Email: alali@bsuedu.ru
ORCID iD: 0000-0003-4370-6719

PhD Student

Russian Federation, 85, Pobeda St., Belgorod, 308015

Walid M. Khaddam

Homs University

Email: wkhaddam@homs-univ.edu.sy
ORCID iD: 0000-0001-6771-2211

Doctor of Microbiology

Syrian Arab Republic, Homs

Mikhail I. Churnosov

Belgorod State National Research University

Email: churnosov@bsuedu.ru
ORCID iD: 0000-0003-1254-6134

Dr. Med. Sci., Professor, Head of the Department of Medical and Biological Disciplines

Russian Federation, 85, Pobeda St., Belgorod, 308015

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