Contraception in women with autoimmune pathology


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Abstract

The paper gives data on the status of the lymphocytic link of the immune system and the impact of hormonal contraception with Regulon for 6 months on some cellular and humoral immunological parameters in thirty-five 18-49-year-old women with autoimmune thyroiditis. Before use of the agent, all cellular and humoral immunological parameters (other than antithyroid antibodies) corresponded to the standard values. After its use, T killer cells, T helper cells, natural killer cells, and antithyroid antibodies to thyroid peroxidase and thyreoglobulin tended to decrease. No changes were found in the values of anti-double-stranded and single-stranded DNA antibodies and anti-nuclear factor. It is indicated that Regulon is likely to affect some immune system links that are implicated in the pathogenesis of autoimmune thyroiditis and, in many women, to improve the course of the disease.

About the authors

A N Akopyan

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Russian Agency for Medical Technologies, Moscow

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Russian Agency for Medical Technologies, Moscow

I V Menzhinskaya

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Russian Agency for Medical Technologies, Moscow

Email: menirvl@mail.ru
Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Russian Agency for Medical Technologies, Moscow

L V Krechetova

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Russian Agency for Medical Technologies, Moscow

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Russian Agency for Medical Technologies, Moscow

M M Ziganshina

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Russian Agency for Medical Technologies, Moscow

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Russian Agency for Medical Technologies, Moscow

Ye A Mezhevitinova

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Russian Agency for Medical Technologies, Moscow

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Russian Agency for Medical Technologies, Moscow

G T Sukhikh

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Russian Agency for Medical Technologies, Moscow

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Russian Agency for Medical Technologies, Moscow

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