CLINICAL AND LABORATORY STUDIES IN PATIENTS WITH NEUROLOGICAL COMPLICATIONS OF ECLAMPSIA


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Abstract

Objective. To make a frequency analysis of the results of laboratory tests in pregnant women with eclampsia accompanied by neurological complications and to reveal the laboratory parameters characteristic for the pathology studied. Material and methods. The cases of neurological complications in eclampsia, published in English-language medical journals from 1980 to 2008, were analyzed. Results. In the obtained sample, the mean value of aspartate aminotransferase considerably exceeds the upper limit of the reference range for this indicator. This can suggest that the pathology in question is practically always attended by liver dysfunctions; however, the degree of the latter can greatly vary. The plasma creatinine value, reflecting the preservation of kidney function in particular, is within or above the upper reference range in more than one-third of the patients with this pathology. The count of platelets was below 150*10 6/l in 30.4% of the total number of patients and less than 100*10 6/l in half (15.2%) of them. Conclusion. The preliminary results obtained in rather heterogeneous and biased samples can suggest that impairments occur not only in different structures of the brain in cases of neurological complications of eclampsia.

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About the authors

E. M SHIFMAN

Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia

Email: e_shifman@oparina4.ru
Moscow

G. P TIKHOVA

Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia

Moscow

T. Yu IVANETS

Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia

Moscow

S. E FLOKA

Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia

Moscow

D. M AKIMOVA

Republican Clinical Hospital, Maternity Home Three

Makhachkala

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