EXPERIENCE WITH EFFERENT METHODS USED IN THE TREATMENT OF SEVERE HYPERLIPIDEMIA IN A PREGNANT WOMAN
- Authors: FEDOROVA T.A1, ROGACHEVSKY O.V1, ORDZHONIKIDZE N.V1, TKACHEVA O.N1, MITRYA I.V1
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Affiliations:
- Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia
- Issue: No 2 (2012)
- Pages: 90-92
- Section: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/246744
- ID: 246744
Cite item
Abstract
Objective. To evaluate the efficiency of using plasmapheresis (PA) and cascade plasma filtration (CPF) in a pregnant woman with severe hyperlipidemia. Subjects and methods. The paper describes a clinical observation of a female patient diagnosed as having 33—34-week pregnancy, chronic placental insufficiency, decompensated type 1 diabetes mellitus, diabetic micro- and macroangiopathy, hepatic steatosis, hyperlipidemia, and chronic pyelonephritis. She was treated with 3 PA sessions on a PSA-2 device (Haemonetics, USA) and 2 CPF sessions on a Cobe Spectra apparatus (Frezenius, Germany) with an Evaflux 5a filter (Kuraray, Japan). Clinical, biochemical, hemostasiological, and ultrasound studies were used. Results. There was a significant reduction in the lipid spectrum parameters: the levels of cholesterol, triglycerides, low-density lipoproteins, and thrombodynamic potential after a course of therapeutic PA and CPF. At 36 weeks gestation, the patient gave birth to a baby by cesarean section. The boy was alive, 47 cm in length, weighed 2359 g, with Apgar scores of 7/8. Conclusion. Efferent hemocorrection techniques should be considered as the methods of choice in treating pregnant women with obvious metabolic disturbances to prevent fatal pancreatitis and severe obstetric complications.
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About the authors
T. A FEDOROVA
Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia
Email: tfedorova1@mail.ru
Moscow
O. V ROGACHEVSKY
Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of RussiaMoscow
N. V ORDZHONIKIDZE
Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of RussiaMoscow
O. N TKACHEVA
Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of RussiaMoscow
I. V MITRYA
Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of RussiaMoscow
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