THE SPECIFIC FEATURES OF A PERINATAL HISTORY IN NEWBORN INFANTS WITH MULTIORGAN DYSFUNCTION


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Abstract

Objective. To study the specific features of a perinatal history in newborn infants with multiorgan dysfunction (MOD) in relation to its severity and outcome. Subject and methods. The investigation enrolled 453 neonatal infants with moderate (n=175) and severe (n=197) manifestations of MOD and its fatal outcome (n=81). Results. There was a preponderance of premature infants among the neonates with MOD. The latter’s mothers had frequently somatic, obstetric, or gynecological histories and pathological pregnancy. Birth asphyxia occurred in more than 95% of the neonates with MOD and extremely low birth weight. Conclusion. The somatic and obstetric/gynecological histories and the course of pregnancy increase the risk of MOD; the degree of asphyxia determines the severity of MOD; and birth weight impacts the outcome of MOD in newborn infants.

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About the authors

E. N SEREBRYAKOVA

South Ural State Medical University, Ministry of Health of Russia

Email: doctor-hit@yandex.ru
Department of Hospital Pediatrics, Clinical Immunology, and Allergology

D. K VOLOSNIKOV

South Ural State Medical University, Ministry of Health of Russia

Email: dk_vol@mail.ru
Department of Hospital Pediatrics, Clinical Immunology, and Allergology

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