Possibilities for the treatment of iron-deficiency anemia in third-trimester pregnancy


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Objective. To evaluate effectiveness of treatment of mild and moderate iron deficient anemia in the third trimester of pregnancy with preparation ferro-folgamma using haematologic and biochemical tests. Subject and methods. Haematologic: number of erythrocytes, contents of haemoglobin, mean corpuscular volume, mean corpuscular haemoglobin, red cell distribution width and biochemical tests: serum iron and ferritin were studied in 54 pregnant women before and at 4 and 6 weeks of treatment with ferro-folgamma. Results. Treatment with ferro-folgamma produces substantial increase in haematological and biochemical tests in pregnant women in the third trimester and corrects iron deficient anemia properly according to referent levels. Ferritin as acute phase protein does not reflect iron deficient state in pregnant women. Conclusion. Studied haematologic tests: number of erythrocytes, contents of haemoglobin, mean corpuscular volume, mean corpuscular haemoglobin, red cell distribution width could be used for the control of efficiency of treatment with iron containing preparations. Ferritin as acute phase protein does not reflect iron deficient state in pregnant women.

Full Text

Restricted Access

About the authors

V. A Petrukhin

Moscow Regional Scientific Research Institute of Obstetrics and Gynecology

Email: lakmoniiag@mail.ru
MD, professor, Head of Obstetrics Physiological Department

A. P Melnikov

Moscow Regional Scientific Research Institute of Obstetrics and Gynecology

Email: lakmoniiag@mail.ru
PhD, Senior Researcher of Obstetrics Physiological Department

T. S Budykina

Moscow Regional Scientific Research Institute of Obstetrics and Gynecology

Email: budit@mail.ru
MD, Head of Clinical Diagnostic Laboratory

V. L Grishin

Moscow Regional Scientific Research Institute of Obstetrics and Gynecology

Email: victor_grishin@gmail.com
PhD, Senior Researcher of Clinical Diagnostic Laboratory

References

  1. Лаптев В.В., Токарев Ю.Н., Максимов В.А. Клинико-физиологические основы и безопасность компонентной терапии эритроцитами. Краткое пособие для врачей. М.: Издательское товарищество «АдамантЪ»; 2008. 296 с
  2. Краснополъский В.И., Логутова Л.С., Серова О.Ф., Петрухин В.А., Туманова В.А., Шаповаленко С.А. и др. Лечение железодефицитных анемий у беременных женщин. Информационно-методическое письмо. М.; 2004. 22 с
  3. Pavord S., Hunt B., eds. The obstetric hematology manual. New York: Cambridge University Press; 2010. 266 p
  4. Рагимов А.А., Байрамалибейли И.Э. Основы диагностики, профилактики и лечения анемий. М.: ГОУ ВУНМЦ МЗ РФ; 2002. 288 с
  5. Бокарев И.Н. Внутренние болезни: дифференциальная диагностика и лечение: учебник. М.: «Медицинское информационное агентство»; 2009. 1004 с
  6. Петрухин В., Павлова Т., Жиляева О., Мельников А. Лечение анемии у беременных с использованием препарата «Ферро-Фольгамма». Врач. 2009; 8: 30-2

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2014 Bionika Media

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies