Possibilities for the treatment of iron-deficiency anemia in third-trimester pregnancy


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Objective. To evaluate effectiveness of treatment of mild and moderate iron deficient anemia in the third trimester of pregnancy with preparation ferro-folgamma using haematologic and biochemical tests. Subject and methods. Haematologic: number of erythrocytes, contents of haemoglobin, mean corpuscular volume, mean corpuscular haemoglobin, red cell distribution width and biochemical tests: serum iron and ferritin were studied in 54 pregnant women before and at 4 and 6 weeks of treatment with ferro-folgamma. Results. Treatment with ferro-folgamma produces substantial increase in haematological and biochemical tests in pregnant women in the third trimester and corrects iron deficient anemia properly according to referent levels. Ferritin as acute phase protein does not reflect iron deficient state in pregnant women. Conclusion. Studied haematologic tests: number of erythrocytes, contents of haemoglobin, mean corpuscular volume, mean corpuscular haemoglobin, red cell distribution width could be used for the control of efficiency of treatment with iron containing preparations. Ferritin as acute phase protein does not reflect iron deficient state in pregnant women.

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作者简介

V. Petrukhin

Moscow Regional Scientific Research Institute of Obstetrics and Gynecology

Email: lakmoniiag@mail.ru
MD, professor, Head of Obstetrics Physiological Department

A. Melnikov

Moscow Regional Scientific Research Institute of Obstetrics and Gynecology

Email: lakmoniiag@mail.ru
PhD, Senior Researcher of Obstetrics Physiological Department

T. Budykina

Moscow Regional Scientific Research Institute of Obstetrics and Gynecology

Email: budit@mail.ru
MD, Head of Clinical Diagnostic Laboratory

V. Grishin

Moscow Regional Scientific Research Institute of Obstetrics and Gynecology

Email: victor_grishin@gmail.com
PhD, Senior Researcher of Clinical Diagnostic Laboratory

参考

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