THE FETOPLACENTAL UNIT IN DIFFERENT TYPES OF IMPAIRED VILLOUS TREE FORMATION

Objective. To study the specific features of the fetoplacental unit in different types of impaired villous tree formation. Subjects and methods. One hundred and nineteen pregnant women were examined. Group 1 (control) comprised 33 women with the villous tree normal in structure. Group included 43 cases with abnormally formed terminal villi (Subgroup 2A of 27 patients with terminal villous deficiency and relatively normally developed stroma and vessels; Subgroup 2B of 16 patients with significant stromal sclerosis and vascular reduction). Group 3 consisted of 43 women with the immature villous tree (Subgroup 3A of 30 cases with a preponderance of differentiated intermediate villi; Subgroup 3B of 13 patients with a predominance of undifferentiated intermediate villi). The results of ultrasonography, Doppler study, and cardiotocography were comparatively analyzed. Results. No statistically significant differences were found in the parameters between the control and compared study groups when estimating the maturity and thickness of the placenta, the amount of amniotic fluid, blood flow in the uterine artery, fetal middle cerebral artery, and aorta and when performing cardiotocography in the third trimester. There was a statistically significant reduction in umbilical artery blood flow in the women with a prevalence of undifferentiated intermediate villi.

placental insufficiency, intrauterine growth retardation, impaired villous tree formation