THE FIRST ALL-RUSSIAN PHARMACOEPIDEMIOLOGICAL STUDY «EPIDEMIOLOGY OF DRUG USE IN PREGNANT WOMEN»: BASIC RESULTS

Objective. To study drug-prescribing tactics for pregnant women in different regions of Russia. Subjects and methods. A one-stage multicenter pharmacoepidemiological study was conducted. Questionnaire surveys were made among 1286 physicians of different specialties and 2324 pregnant women and puerperas. Results. Most physicians have been shown to be inadequately aware of the processes of organogenesis. It has been ascertained that the physicians prescribe a wide range of drugs to pregnant women and recommend drugs with unstudied safety to a fetus and those that are contraindicated in pregnancy. The pregnant women show a low adherence to the prescribed therapy and a high self-treatment rate. Subjects and methods. A one-stage multicenter pharmacoepidemiological study was conducted. Questionnaire surveys were made among 1286 physicians of different specialties and 2324 pregnant women and puerperas. Conclusion. It is necessary to update branch standards and to introduce pregnancy management protocols according to the data of evidence-based medicine, to adjust drug use instructions in accordance with updated clinical recommendations, to elaborate educational programs for the therapy of somatic diseases in pregnancy for physicians of different specialties, to set up an effectively operating pharmacovigilance system to monitor adverse reactions occurring with drug use in pregnancy, and to initiate the creation and maintenance of registers for using drugs in pregnant women.

pharmacoepidemiology, pregnancy