Noninvasive prenatal diagnosis of aneuploidies by extracellular DNA sequencing: The current view on the problem


Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Рұқсат ақылы немесе тек жазылушылар үшін

Аннотация

The article sets forth the current views on noninvasive prenatal diagnosis (NPD) by sequencing to determine aneuploidies in both high- and low-risk pregnant women. It describes the results of the investigations conducted in the past 3 years, which determine the sensitivity, specificity and accuracy of tests versus conventional screening methods in pregnant women. The advantages and limitations of NPD methods and the opinions of leading obstetrics societies on whether it is expedient to use them as diagnostic and screening tools are defined.

Толық мәтін

Рұқсат жабық

Авторлар туралы

N. Tetruashvili

Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: tetrauly@mail.ru
Doctor of Medicine, Head of the Department of Pregnancy Loss Prevention and Therapy

N. Parsadanyan

Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Graduate student, Department of Pregnancy Loss Prevention and Therapy

N. Fedorova

Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: natasha_fedorova@mail.ru
candidate of Medicine, obstetrician-gynecologist

D. Trofimov

Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: d_troflmov@oparina4.ru
Ph.D. in medical sciences, Head of Laboratory of molecular genetic methods

E. Shubina

Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: e_shubina@oparina4.ru
Graduate student, laboratory of molecular genetic methods

Әдебиет тізімі

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