Extraplacental trophoblast structures: Study, structure, functions, properties, diagnostic and therapeutic value


Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Рұқсат ақылы немесе тек жазылушылар үшін

Аннотация

Objective. To make a systematic analysis of the data available in the current literature on extraplacental trophoblast elements in the maternal body, the history of their study, properties, and the possibilities of therapeutic and diagnostic use. Material and methods. The review included the data of foreign and Russian articles published in the past 50 years and found in the retrieval systems Pubmed and Google scholar on this topic. Citation preference was given to the papers published in the past 10 years. Results. Current views on the morphology, classification, functions, and properties of extraplacental trophoblast structures are considered. There are data of in vitro and in vivo experimental studies. Attention is given to the specific features of the therapeutic and diagnostic potential of trophoblast and placental cells, which is determined by their properties (invasion, hormonal function, low immunogenicity, and a capability for immunosuppression and tolerance induction); and views on cancer risk are described. Conclusion. The study of extraplacental trophoblast functions offers prospects for the clinical diagnosis of genetic disorders and the placental status, for the understanding of tolerance forming processes during pregnancy, oncogenesis, and implantation. Mesenchymal stem cells, placental explants, and placental factors may be effectively used in cellular and tissue therapy and, on the strength of their natural trophicity for reproductive organs, are particularly effective in treating gynecological diseases: infertility, endocrine disorders, and autoimmune responses.

Толық мәтін

Рұқсат жабық

Авторлар туралы

Volodimir Prokopyuk

Institute for Problems of Cryobiology and Cryomedicine, National Academy of Sciences of Ukraine

Email: prokopyuk@mail.ru, cryo@online.kharkov.ua
PhD, senior researcher Department of Low Temperature Bank of Biological Objects.

Әдебиет тізімі

  1. Грищенко В.И., Юрченко Т.Н., ред. Плацента: криоконсервирование, структура, свойства, перспективы клинического применения. Харьков: СПД ФЛ Бровин А.В.; 2011. 292с. [Grischenko V.I., Yurchenko T.N., ed. Placenta: cryopreservation, structure, properties, prospects for clinical application. Kharkiv: SPD FL Brovin A.V.; 2011. 292p. (in Russian)]
  2. Martinez-Varea A., Pellicer B., Perales-Marin A., Pellicer A. Relationship between maternal immunological response during pregnancy and onset of preeclampsia. J. Immunol. Res. 2014; 2014: 210241.
  3. Veenstra van Nieuwenhoven A.L., Heineman M.J., Faas M.M. The immunology of successful pregnancy. Hum. Reprod. Update. 2003; 9(4): 347-57.
  4. Khan A., Bulmer J.N., Chantraine F., Chen C.P., Chen Q., Collins S. et al. IFPA Meeting 2012. Workshop Report III: trophoblast deportation, gestational trophoblastic disease, placental insufficiency and fetal growth restriction, trophoblast over-invasion and accreta-related pathologies, placental thrombosis and fibrinolysis. Placenta. 2013; 34(Suppl.): S11-6.
  5. Сухих Г.Т., Каретникова Н.А., Баранова Е.Е., Шубина Е.С., Коростин Д.О., Екимов А.Н., Парсаданян Н.Г., Гус А.И., Бахарев В.А., Трофимов Д.Ю., Воеводин С.М., Тетруашвили Н.К. Неинвазивная пренатальная диагностика анеуплоидий методом высокопроизводительного секвенирования (NGS) в группе женщин высокого риска. Акушерство и гинекология. 2015; 4: 5-10. [Sukhikh G.T., Karetnikova N.A., Baranova E.E., Shubina E.S., Korostin D.O., Ekimov A.N., Parsadanyan N.G., Gus A.I., Bakharev V.A., Trofimov D.Yu., Voevodin S.M., Tetruashvili N.K. Noninvasive prenatal diagnosis of aneuploidies by next-generation sequencing (NGS) in a group of high-risk women. Akusherstvo i ginekologiya/Obstetrics and Gynecology. 2015; 4: 5-10. (in Russian)]
  6. Parolini O., Alviano F., Bagnara G.P., Bilic G., Bühring H.J., Evangelista M. et al. Concise review: isolation and characterization of cells from human term placenta: outcome of the first international Workshop on Placenta Derived Stem Cells. Stem Cells. 2008; 26(2): 300-11.
  7. Schmorl G. Pathologisch-anatomische Untersuchungen ueber PuerperalEklampsie. Leipzig: Verlag von F.C.W. Vogel; 1893. 104S.
  8. Redman C.W., Sargent I.L. Circulating microparticles in normal pregnancy and pre-eclampsia. Placenta. 2008; 29(1): 73-7.
  9. Attwood H.D., Park W.W. Embolism to the lungs by trophoblast. J. Obstet. Gynaecol. Br. Commonw. 1961; 68: 611-7.
  10. Douglas G.W., Thomas L., Carr M., Cullen N.M., Morris R. Trophoblast in thecirculating blood during pregnancy. Am. J. Obstet. Gynecol. 1959; 78: 960-73.
  11. Kozma R., Spring J., Johnson P.M., Adinolfi M. Detection of syncytiotrophoblast in maternal peripheral and uterine veins using a monoclonal antibody and flow cytometry. Hum. Reprod. 1986; 1(5): 335-6.
  12. Askelund K.J., Chamley L.W. Trophoblast deportation part I: Review of the evidence demonstrating trophoblast shedding and deportation during human pregnancy. Placenta. 2011; 32(10): 716-23.
  13. Covone A.E., Mutton D., Johnson P.M., Adinolfi M. Trophoblast cells in peripheral blood from pregnant women. Lancet. 1984; 2(8407): 841-3.
  14. Goodfellow C.F., Taylor P.V. Extraction and identification of trophoblast cells circulating in peripheral blood during pregnancy. Br. J. Obstet. Gynaecol. 1982; 89(1): 65-8.
  15. O’Sullivan M.J., McIntyre J.A., Prior M., Warriner G., Faulk W.P. Identification of human trophoblast membrane antigens in maternal blood during pregnancy. Clin. Exp. Immunol. 1982; 48(1): 279-87.
  16. Chua S., Wilkins T., Sargent I., Redman C. Trophoblast deportation in preeclamptic pregnancy. Br. J. Obstet. Gynaecol. 1991; 98(10): 973-9.
  17. Gupta A., Hasler P., Gebhardt S., Holzgreve W., Hahn S. Occurrence of neutrophil extracellular DNA traps (NETs) in pre-eclampsia: a link with elevated levels of cell-free DNA? Ann. N. Y. Acad. Sci. 2006; 1075: 118-22.
  18. Johansen M., Redman C.W., Wilkins T., Sargent I.L. Trophoblast deportation in human pregnancy - its relevance for pre-eclampsia. Placenta. 1999; 20(7): 531-9.
  19. Hawes C.S., Suskin H.A., Petropoulos A., Latham S.E., Mueller U.W. A morphologic study of trophoblast isolated from peripheral blood of pregnant women. Am. J. Obstet. Gynecol. 1994; 170(5, Pt 1): 1297-300.
  20. Lo Y.M., Leung T.N., Tein M.S., Sargent I.L., Zhang J., Lau T.K. et al. Quantitative abnormalities of fetal DNA in maternal serum in preeclampsia. Clin. Chem. 1999; 45(2): 184-8.
  21. Huppertz B., Kadyrov M., Kingdom J.P. Apoptosis and its role in the trophoblast. Am. J. Obstet. Gynecol. 2006; 195(1): 29-39.
  22. Ishihara N., Matsuo H., Murakoshi H., Laoag-Fernandez J.B., Samoto T., Maruo T. Increased apoptosis in the syncytiotrophoblast in human term placentas complicated by either preeclampsia or intrauterine growth retardation. Am. J. Obstet. Gynecol. 2002; 186(1): 158-66.
  23. Pantham P., Askelund K.J., Chamley L.W. Trophoblast deportation part II: a review of the maternal consequences of trophoblast deportation. Placenta. 2011; 32(10): 724-31.
  24. Billingham R.E., Sparrow E.M. The effect of prior intravenous injections of dissociated epidermal cells and blood on the survival of skin homografts in rabbits. J. Embryol. Exp. Morphol. 1955; 3(3): 265-85.
  25. Прокопюк В.Ю., Прокопюк О.С., Мусатова И.Б., Шевченко Н.А., Роенко А.А., Терехова Е.А., Волина В.В. Оценка сохранности эксплантов плаценты, пуповины и плодных оболочек после криоконсервирования. Клеточная и органная трансплантология. 2015; 3(1): 34-8. [Prokopyuk V.Yu., Prokopyuk O.S., Musatova I.B., Shevchenko N.A., Roenko A.A., Terehova E.A., Volina V.V. Evaluation of the safety of placental explants, umbilical cord and membranes after cryopreservation. 2015; 3(1): 34-8. (in Russian)]
  26. Tedeschi L.G., Tedeschi C.G. Experimental trophoblastic embolism and hyperplasminemia. Arch. Pathol. 1963; 76: 387-97.
  27. Schumacher A., Costa S.D., Zenclussen A.C. Endocrine factors modulating immune responses in pregnancy. Front. Immunol. 2014; 5: 196.
  28. Chamley L.W., Chen Q., Ding J., Stone P.R., Abumaree M. Trophoblast deportation: just a waste disposal system or antigen sharing? J. Reprod. Immunol. 2011; 88(2): 99-105.
  29. Abumaree M.H., Stone P.R., Chamley L.W. The effects of apoptotic, deported human placental trophoblast on macrophages: possible consequences for pregnancy. J. Reprod. Immunol. 2006; 72(1-2): 33-45.
  30. Mincheva-Nilsson L., Baranov V. Placenta-derived exosomes and syncytiotrophoblast microparticles and their role in human reproduction: immune modulation for pregnancy success. Am. J. Reprod. Immunol. 2014; 72(5): 440-57.
  31. Прокопюк О.С., Шевченко Н.О., Прокопюк В.Ю., Чуб О.В., Терехова О.О. Вплив кріоконсервованих біооб’єктів плацентарного походження на культуру клітин. Вісник проблем біології і медицини. 2015; 122(1): 160-4. [Prokopyuk O.S., Shevchenko N.O., Prokopyuk V.Yu., Chub O.V., Terehova O.O. The impact of cryopreserved biological objects placental origin in cell culture. Bulletin problems of biology and medicine. 2015; 122 (1): 160-4. (in Ukrainian)]
  32. Park W.W. Experimental trophoblastic embolism of the lungs. J. Pathol. Bacteriol. 1958; 75(2): 257-65.
  33. Lau S., Guild S.J., Barrett C.J., Malpas S.C., Chamley L. Injection of necrotic trophoblastic cells increased blood pressure in the final third of gestation in rats. Placenta. 2010; 31(9): A137.
  34. Гольцев А.Н., Юрченко Т.Н., ред. Плацента: криоконсервирование, клиническое применение. Харьков: СПД ФЛ Бровин А.В.; 2012. 318с. [Goltsev A.N. Yurchenko T.N., ed. Placenta: cryopreservation, clinical application. Kharkiv: SPD FL Brovin A.V.; 2012. 318p. (in Russian)]
  35. Pipino C., Shangaris P., Resca E., Zia S., Deprest J., Sebire N.J. et al. Placenta as a reservoir of stem cells: an underutilized resource? Br. Med. Bull. 2013; 105: 43-68.
  36. Thirumala S., Goebel W.S., Woods E.J. Clinical grade adult stem cell banking. Organogenesis. 2009; 5(3): 143-54.
  37. Pogozhykh D., Prokopyuk V., Pogozhykh O., Mueller T., Prokopyuk O. Influence of factors of cryopreservation and hypothermic storage on survival and functional parameters of multipotent stromal cells of placental origin. PLoS One. 2015 Oct 2; 10 (10).
  38. Астрелина Т.А., Гомзяков А.Е., Кобзеева И.В., Карпова Е.Э., Круглова Я.А., Скоробагатова Е.В. и др. Оценка качества и безопасности применения криоконсервированных мультипотентных мезенхимальных стромальных клеток плаценты человека в клинической практике. Клеточная трансплантология и тканевая инженерия. 2013; 8(4): 82-6. [Astrelina T.A., Gomzyakov A.E., Kobzeeva I.V., Karpova E.E., Kruglova Ya.A., Skorobagatova E.V. et al. Evaluation of the quality and safety of cryopreserved human multipotent mesenchymal stromal cells of the placenta in clinical practice. Kletochnaya transplantologiya i tkanevaya inzheneriya. 2013; 8(4): 82-6. (in Russian)]
  39. Melmed G.Y., Pandak W.M., Casey K., Abraham B., Valentine J., Schwartz D. et al. Human placenta-derived cells (PDA-001) for the treatment of moderate-to-severe crohn’s disease: a phase 1b/2a study. Inflamm. Bowel Dis. 2015; 21(8): 1809-16.
  40. Liu W., Morschauser A., Zhang X., Lu X., Gleason J., He S. et al. Human placenta-derived adherent cells induce tolerogenic immune responses. Clin. Transl. Immunology. 2014; 3(5): e14.
  41. Трифонов В.Ю., Прокопюк В.Ю., Прокопюк О.С., Липина О.В., Волина В.В., Зуб Л.И., Фалько О.В., Прокопюк А.В. Экспериментальное обоснование возможности прегравидарной профилактики антифосфолипидного синдрома. Таврический медико-биологический вестник. 2010; 13(4): 188-92. [Trifonov V.Yu., Prokopyuk V.Yu., Prokopyuk O.S., Lipina O.V., Volina V.V., Zub L.I., Falko O.V., Prokopyuk A.V. Experimental study opportunities pregravid prevention of antiphospholipid syndrome. Tavricheskiy mediko-biologicheskiy vestnik. 2010; 13(4): 188-92. (in Russian)]
  42. Паукер В.А., Шмаков Р.Г. Онкологические заболевания и беременность. Акушерство и гинекология. 2013; 11: 5-10. [Pauker W.A., Shmakov R.G. Cancer and pregnancy. Akusherstvo i ginekologiya/Obstetrics and Gynecology. 2013; 11: 5-10. (in Russian)]
  43. Ross C.A. The trophoblast model of cancer. Nutr. Cancer. 2015; 67(1): 61-7.
  44. Zhang S., Yuan J., Li W., Ye Q. Organ transplantation from donors (cadaveric or living) with a history of malignancy: review of the literature. Transplant. Rev. (Orlando). 2014; 28(4): 169-75.
  45. Dhanda S., Ramani S., Thakur M. Gestational trophoblastic disease: a multimodality imaging approach with impact on diagnosis and management. Radiol. Res. Pract. 2014; 2014: 842751.
  46. Zhang D., Zheng L., Shi H., Chen X., Wan Y., Zhang H. et al. Suppression of peritoneal tumorigenesis by placenta-derived mesenchymal stem cells expressing endostatin on colorectal cancer. Int. J. Med. Sci. 2014; 11(9): 870-9.
  47. Dhallan R., Au W.C., Mattagajasingh S., Emche S., Bayliss P., Damewood M. et al. Methods to increase the percentage of free fetal DNA recovered from the maternal circulation. JAMA. 2004; 291(9): 1114-9.
  48. Legier T.J., Liu Z., Mavrou A., Finning K., Hromadnikova I., Galbiati S. et al. Workshop report on the extraction of foetal DNA from maternal plasma. Prenat. Diagn. 2007; 27(9): 824-9.
  49. Benn P., Curnow K.J., Chapman S., Michalopoulos S.N., Hornberger J., Rabinowitz M. An economic analysis of cell-free DNA non-invasive prenatal testing in the US general pregnancy population. PLoS One. 2015; 10(7): 0132313.
  50. Walker B.S., Nelson R.E., Jackson B.R., Grenache D.G., Ashwood E.R., Schmidt R.L. A cost-effectiveness analysis of first trimester non-invasive prenatal screening for fetal trisomies in the United States. PLoS One. 2015; 10(7): 0131402.

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