PSYCHOEMOTIONAL STATUS AND CHANGES IN THE HORMONAL PROFILE OF PREGNANT WOMEN


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Аннотация

Objective. To assess the psychoemotional status-hormonal profile relationships in women during pregnancy. Subjects and methods. 65 pregnant women at 26-32 weeks’ gestation were examined. The examinees’ mean age was 26.9±0.95 years. The psychoemotional status of the pregnant women was evaluated using structured interviews, questioning, and psychological tests. The plasma concentrations of prolactin (Pr), cortisol (K), insulin (I), and dehydroepiandrosterone sulfate (DHEAS) were quantitated by enzyme immunoassay on a SIRIO S device, by applying DRG (USA) and Monobind Inc (USA) test systems. Results. The results of the performed investigation could establish a predominance of moderate and high (69.2%) over low (30.8%) situational anxiety (SA) among the pregnant women of the examined groups. At the same time more than 90% of the pregnant women had trait anxiety. In the pregnant women with high and moderate SA, cortisol levels and K/I ratio were statistically significantly higher (p < 0.05) than those in the pregnant women with low SA. The levels of Pr and DHEAS were found to be statistically significantly higher (p < 0.05) among the patients with high and moderate SA than those in the control group of patients with low SA. Conclusion. The results of the performed investigation may be suggestive of the compensatory role of elevated DHEAS and Pr levels in reference to the rise of K in pregnant women, which should be regarded as a mechanism of adaptation to stresses during pregnancy.

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Авторлар туралы

Vladimir Syusyuka

Zaporozhye State Medical University

Email: svg.zp@i.ua
PhD of Medical Science, Assistant Professor of Department of Obstetrics and Gynaecology 69035, Ukraine, Zaporozhye, Mayakovsky avenue 26

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