Synergy between folates and docosahexaenoic acid when taking the micronutrients separately during pregnancy


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Аннотация

The synergy between folates and omega-3 polyunsaturated fatty acids (omega-3 PUFA) is due to the fact that both micronutrients may reduce chronic inflammation and are important for the normal physiological development of the fetus. Folate deficiency disrupts DNA methylation and results in functional omega-3 PUFA deficiency in pregnant women, whereas omega-3 PUFA deficiency stimulates folate metabolic disturbances. Docosahexaenoic acid (DHA) is one of the most important types of PUFA for pregnant women. The combined use of folic acid and DHA together with other fat-soluble vitamins (D, E) is promising for nutritional support during pregnancy.

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Авторлар туралы

Olga Gromova

Federal Research Center of Informatics and Management, Russian Academy of Sciences

Email: unesco.gromova@gmail.com
Professor, Doctor of Medical Sciences, Science №ad of the Institute of Pharmacoinformatics, leading researcher of the Department of Intellectual Systems

Ivan Torshin

Federal Research Center of Informatics and Management, Russian Academy of Sciences

PhD in Applied Mathematics, PhD in Chemistry, Senior researcher in Laboratory of Pharmacoinformatics at the Department of Intellectual Systems

Nana Tetruashvili

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology

Email: n_tetruashvili@oparina4.ru
Doctor of Medicine, Head of the Department of Pregnancy Loss Prevention and Therapy

Ivan Reier

Federal Research Center of Informatics and Management, Russian Academy of Sciences

PhD, Senior researcher in Laboratory of Pharmacoinformatics at the Department of Intellectual Systems

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