Experience in treating early toxicosis of pregnancy


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Ашық рұқсат Ашық рұқсат
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Рұқсат жабық Рұқсат ақылы немесе тек жазылушылар үшін

Аннотация

Ginger (Zingiber officinale) has gained widespread acceptance in culinary practice and is often used as a food additive, improving the taste of products. It is also a well-known and well-proven nonpharmacological agent for pregnant women, which is used to treat nausea and vomiting. The highest-quality numerous studies and publications (Medline, PubMed) (randomized double-blind placebo-controlled studies, meta-analyses) show the efficacy and safety of ginger-containing agents used in pregnant women, while any risks to the mother and her unborn child have not been found. In vivo studies have shown no toxicity of the agent. The available data demonstrate the safety and efficacy of ginger for early toxicosis in pregnancy.

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Авторлар туралы

Grigoriy Slizovsky

Siberian State Medical University

Email: sgv5858@mail.ru
MD, Associate Professor, Head. Department of Pediatric Surgical Diseases

Ivan Kuzhelivsky

Siberian State Medical University

Email: kuzhel@rambler.ru
Ph.D., Associate Professor of the Department of Pediatric Surgical Diseases

Yana Shikunova

Siberian State Medical University

Email: sgv5858@mail.ru
Ph.D., Associate Professor of the Department of Pediatric Surgical Diseases

Yulia Sigareva

Siberian State Medical University

Email: julsigareva@gmail.com
6th year student of the medical faculty

Әдебиет тізімі

  1. Sukandar E., Qowiyah A., Purnamasari R. Teratogenicity study of combination of ginger rhizome extract and noni fruit extract in Wistar rat. Indones. J. Pharm. 2009; 20(1): 48-54.
  2. Plengsuriyakarn T., Viyanant V., Eursitthichai V., Tesana S., Chaijaroenkul W., Itharat A., Na-Bangchang K. Cytotoxicity, toxicity, and anticancer activity of Zingiber officinale Roscoe against cholangiocarcinoma. Asian J. Cancer Prev. 2012; 13(9): 4597-606.
  3. Wang Y., Yu H., Zhang X., Feng Q., Guo X., Li S. et al. Evaluation of daily ginger consumption for the prevention of chronic diseases in adults: a cross-sectional study. Nutrition. 2017; 36: 79-84.
  4. Petersen I., McCrea R.L., Lupattelli A., Nordeng H. Women’s perception of risks of adverse fetal pregnancy outcomes: a large-scale multinational survey. BMJ Open. 2015; 5: e007390.
  5. Sharifzadeh F., Kashanian M., Koohpayehzadeh J., Rezaian F., Sheikhansari N., Eshraghi N. A comparison between the effects of ginger, pyridoxine (vitamin B6) and placebo for the treatment of the first trimester nausea and vomiting of pregnancy (NVP). J. Matern. Fetal Neonatal Med. 2018; 31(19): 2509-14.
  6. Heitmann K., Nordeng H., Holst L. Safety of ginger use in pregnancy: results from a large population-based cohort study. Eur. J. Clin. Pharmacol. 2013; 69(2): 269-77.
  7. Choi J.S., Han J.Y., Ahn H.K., Lee S.W., Koong M.K., Velazquez-Armenta E.Y., Nava-Ocampo A.A. Assessment of fetal and neonatal outcomes in the offspring of women who had been treated with dried ginger (Zingiberis rhizoma siccus) for a variety of illnesses during pregnancy. J. Obstet. Gynaecol. 2015; 35(2): 125-30.
  8. Boltman-Binkowski H. A systematic review: Are herbal and homeopathic remedies used during pregnancy safe? Curationis. 2016; 39(1): 1514.
  9. Saberi F., Sadat Z., Abedzadeh-Kalahroudi M., Taebi M. Acupressure and ginger to relieve nausea and vomiting in pregnancy: a randomized study. Iran. Red Crescent Med. J. 2013; 15(9): 854-61.
  10. Saberi F., Sadat Z., Abedzadeh-Kalahroudi M., Taebi M. Effect of ginger on relieving nausea and vomiting in pregnancy: a randomized, placebo-controlled trial. Nurs. Midwifery Stud. 2014; 3(1): e11841.
  11. Ensiyeh J., Sakineh M.A. Comparing ginger and vitamin B6 for the treatment of nausea and vomiting in pregnancy: a randomised controlled trial. Midwifery. 2009; 25(6): 649-53.
  12. Mohammadbeigi R., Shahgeibi S., Soufizadeh N., Rezaiie M., Farhadifar F. Comparing the effects of ginger and metoclopramide on the treatment of pregnancy nausea. Pak. J. Biol. Sci. 2011; 14(16): 817-20.
  13. Basirat Z., Moghadamnia A., Kashifard M., Sharifi-Ravazi A. The effect of ginger biscuit on nausea and vomiting in early pregnancy. Acta Med. Iran. 2009; 47(1): 51-6.
  14. Ding M., Leach M., Bradley H. The effectiveness and safety of ginger for pregnancy-induced nausea and vomiting: a systematic review. Women Birth. 2013; 26(1): e26-30.
  15. Campbell K., Rowe H., Azzam H., Lane C.A. The management of nausea and vomiting of pregnancy. J. Obstet. Gynaecol. Can. 2016; 38(12): 1127-37.

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