Current progress of genetic and epigenetic studies of cerebral palsy
- Авторлар: Chen S.1,2,3,4, Nanbert Z.5,6,7
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Мекемелер:
- Beijing Pediatric Research Institute
- Beijing Children's Hospital
- Capital Medical University
- National Center for Children's Health
- Nanfang Hospital, Southern Medical University
- The Third Affiliated Hospital, Guangzhou Medical University
- New York State Institute for Basic Research in Developmental Disabilities
- Шығарылым: № 6 (2019)
- Беттер: 94-101
- Бөлім: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/248555
- DOI: https://doi.org/10.18565/aig.2019-6.94-101
- ID: 248555
Дәйексөз келтіру
Аннотация
Cerebral palsy (CP) is a heterogeneous condition, with cases sharing the common feature of non-progressive dysfunction of movement and posture. Although widely studied, the etiology of CP is not yet well understood. It is believed that most cases of CP arise from intrauterine injury to the developing brain. Increasing evidence suggests that (epi)genetic factors might collectively account for a large number of CP cases. In this mini-review, we focus mainly on the genetic and epigenetic aspects of recent progress in understanding the etiology of CP.
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Авторлар туралы
Shen Chen
Beijing Pediatric Research Institute; Beijing Children's Hospital; Capital Medical University; National Center for Children's Health
Email: shenchenlll0@l26.com
Zhong Nanbert
Nanfang Hospital, Southern Medical University; The Third Affiliated Hospital, Guangzhou Medical University; New York State Institute for Basic Research in Developmental Disabilities
Email: Nanbert.Zhong@opwdd.ny.gov
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