CLINICAL AND ECONOMIC EFFECTIVENESS OF A PLACENTAL a-MICROGLOBULIN-1 TEST AND THAT OF THE CLINICAL DIAGNOSIS OF PREMATURE RUPTURE OF MEMBRANES


Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Рұқсат ақылы немесе тек жазылушылар үшін

Аннотация

The incidence of premature rupture of membranes (PROM) during full-term and preterm pregnancy is 10 and 40%, respectively. To clarify the diagnosis of PROM in clinical practice, tests are used, which have a high frequency of false-positive results, being accompanied by unreasonable economic costs. At the same time, new biochemical markers of high accuracy have been developed. Objective: to compare the clinical and economic efficacy of traditional clinical examination and a placental alpha-microglobulin-1 (PAMG-1) test in patients with a presumptive diagnosis of PROM. Subjects and methods. The investigation enrolled 114 women with a presumptive diagnosis of PROM. A decisionmaking model was developed and the cost-effectiveness of traditional tactics and the PAMG-1 test were compared. Results. The cost of a case with the traditional survey strategy was 16,700 rubles. That of the PAMG-1 test was 3,000 rubles. The average cost of a case when using the latter was 3,060 rubles. The average cost saving per patient was 13,640 rubles. Conclusion. Compared with the traditional approach to diagnosing PROM, the use of the PAMG-1 test is more effective and cost-effective.

Толық мәтін

Рұқсат жабық

Авторлар туралы

Oleg Baev

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia; I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia

Email: metod_obsgyn@hotmail.com
MD; Head, Maternity Department One; Department of Obstetrics, Gynecology, and Reproductology 4, Academician Oparin Street, Build. 1, Moscow 117513, Russia

Oleg Tysyachnyi

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: olti23@mail.ru
Cand. Med. Sci.; Researcher, Department of Innovative Technologies 4, Academician Oparin St., Build. 1, Moscow 117513, Russia

Vladimir Klimov

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: va_klimov@oparina4.ru
Cand. Med. Sci.; Head, Service for Organization of Medical Care and Information Service 4, Academician Oparin St., Build. 1, Moscow 117513, Russia

Ivan Balashov

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: i_balashov@oparina4.ru
Junior Researcher Laboratory of Bioinformatics 4, Academician Oparin St., Build. 1, Moscow 117513, Russia

Әдебиет тізімі

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  8. Di Renzo G.C., Roura L.C., Facchinetti F., Antsaklis A., Breborowicz G., Gratacos E. et al. Guidelines for the management of spontaneous preterm labor: identification of spontaneous preterm labor, diagnosis of preterm premature rupture of membranes, and preventive tools for preterm birth. J. Matern. Fetal Neonatal Med. 2011; 24(5): 659-67.
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