Effect of preconceptional cervical electroconizationon the course of pregnancy and childbirth

Мұқаба

Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Рұқсат ақылы немесе тек жазылушылар үшін

Аннотация

Objective: This study aimed to investigate the impact of preconceptional cervical electroconization on the course of pregnancy and childbirth.

Materials and methods: This study compared the pregnancy course and birth outcomes of women who underwent preconceptional electroconization (n=50) with those without cervical pathology (n=48). Statistical analysis was performed using descriptive statistics in an Excel spreadsheet, and comparative analysis was conducted using Fisher's exact test.

Results: Among the pregnant women with a history of cervical electroconization, 34% had cardiovascular disease, 32% had gastrointestinal disease, 14% had neurological disease, 6% had Rh-negative blood, 14% had myomas, 10% were infertile, and 4% had congenital genital malformations. Women with a history of cervical electroconization were more likely to experience isthmic cervical insufficiency (10%) during pregnancy. The percentage of preterm births was higher in women with a history of cervical electroconization than in those without. Labor induction was performed in 22% of the cases, and labor augmentation with oxytocin was performed 7% less frequently than in women without a history of electroconization.

Conclusion: A history of cervical electroconization was associated with a higher prevalence of somatic and gynecological pathologies. However, it did not increase the frequency of cesarean sections or labor induction with oxytocin. No negative effects on the fetus were observed.

Толық мәтін

Рұқсат жабық

Авторлар туралы

Elena Rosyuk

Ural State Medical University, Ministry of Health of the Russian Federation

Хат алмасуға жауапты Автор.
Email: elenakdc@yandex.ru

PhD, Associate Professor, Department of Obstetrics and Gynecology

Ресей, Yekaterinburg

Tatyana Oboskalova

Ural State Medical University, Ministry of Health of the Russian Federation

Email: oboskalova.tat@yandex.ru
ORCID iD: 0000-0003-0711-7896

Dr. Med. Sci., Professor, Head of the Department of Obstetrics and Gynecology

Ресей, Yekaterinburg

Elena Emelyanova

Ural State Medical University, Ministry of Health of the Russian Federation

Email: lena.emelyanova2001@gmail.com

student of the Faculty of Medicine and Prevention

Ресей, Yekaterinburg

Natalya Butorina

Ural State Medical University, Ministry of Health of the Russian Federation

Email: elenakdc@yandex.ru

student of the Faculty of Medicine and Prevention

Ресей, Yekaterinburg

Tatyana Emelyanova

Central City Clinical Hospital No. 6

Email: lena.emelyanova2001@gmail.com

Head of Women’s Consultation No. 1

Ресей, Yekaterinburg

Evgeny Glukhov

Ural State Medical University, Ministry of Health of the Russian Federation; Gynecological Center "Women's Clinic"

Email: dok@gynclinic.ru

Dr. Med. Sci., Professor at the Department of Obstetrics and Gynecology

Ресей, Yekaterinburg; Yekaterinburg

Ekaterina Neff

Gynecological Center "Women's Clinic"

Email: neff@gynclinic.ru

PhD, Deputy Chief Physician

Ресей, Yekaterinburg

Alexander Yakushev

Ural State Medical University, Ministry of Health of the Russian Federation

Email: elenakdc@yandex.ru

PhD, Associate Professor at the Department of Obstetrics and Gynecology

Ресей, Yekaterinburg

Әдебиет тізімі

  1. Kyrgiou M., Athanasiou A., Paraskevaidi M., Mitra A., Kalliala I., Martin-Hirsch P. et al. Adverse obstetric outcomes after local treatment for cervical preinvasive and early invasive disease according to cone depth: systematic review and meta-analysis. BMJ. 2016; 354: i3633. https://dx.doi.org/10.1136/bmj.i3633.
  2. Фириченко С.В., Манухин И.Б., Микаилова Л.У., Мынбаев О.А. Удаленная доля шейки матки и риск преждевременных родов. I Национальный конгресс «Онкология репродуктивных органов: от профилактики и раннего выявления к эффективному лечению», 19-21 мая 2016 года, Москва. Исследования и практика в медицине. 2016; Спецвыпуск: 178. [Firichenko S.V., Manukhin I.B., Mikailova L.U., Mynbayev O.A. Resection of lobe of the cervix and risk of preterm birth. The Ist National Congress "Oncology of reproductive organs: from prevention and early detection to effective treatment", May 19-21, 2016, Moscow. Research’n Practical Medicine Journal. 2016; (Special Issue): 178. (in Russian)].
  3. Yu X., Qie M., Huang L., Hou M. Successful pregnancy in a female with embryonal rhabdomyosarcoma of the cervix who received biopsy and chemotherapy alone without recurrence after 16 years: a case report and literature review. BMC Womens Health. 2023; 23(1): 466. https://dx.doi.org/10.1186/ s12905-023-02623-6.
  4. Министерство здравоохранения Российской Федерации. Клинические рекомендации. Цервикальная интраэпителиальная неоплазия, эрозия и эктропион шейки матки. 2020. 59 c. [Ministry of Health of the Russian Federation. Clinical guidelines. Cervical intraepithelial neoplasia, erosion and ectropion of the cervix. 2020. 59 p. (in Russian)].
  5. Ильина И.Ю., Доброхотова Ю.Э. Совершенствование методов хирургического лечения патологии шейки матки. РМЖ. Мать и дитя. 2022; 5(3): 188-93. [Il’ina I.Yu., Dobrokhotova Yu.E. Optimizing surgical management of uterine cervix disorders. Russian Journal of Woman and Child Health. 2022; 5(3): 188-93 (in Russian)]. https://dx.doi.org/10.32364/ 2618-8430-2022-5-3-188-193.
  6. Паяниди Ю.Г., Боровкова Е.И., Доброхотова Ю.Э., Арутюнян А.М. Тактика ведения беременных с инвазивным раком шейки матки. РМЖ. Мать и дитя. 2019; 2(2): 135-8. [Payanidi Yu.G., Borovkova E.I., Dobrohotova Yu.E., Arutunyan A.M. Managing invasive cervical cancer in pregnancy. Russian Journal of Woman and Child Health. 2019; 2(2): 135-8. (in Russian)]. https://dx.doi.org/10.32364/2618-8430-2019-2-2-135-138.
  7. Бебнева Т.Н., Покуль Л.В. Современные аспекты дифференциального подхода к ведению беременных, отягощенных цервикальными интраэпителиальными неоплазиями. Трудный пациент. 2018; 16(1-2): 22-7. [Bebneva T.N., Pokul L.V. Modern aspects of the differential approach to the management of pregnant women with cervical intraepithelial neoplasias. Difficult Patient. 2018; 16(1-2): 22-7. (in Russian)].
  8. Кузнецова А.И., Петров Ю.А., Ермолова Н.В. Беременность и рак шейки матки. Главный врач Юга России. 2022; 2(83): 25-8. [Kuznetsova A.I., Petrov Yu.A., Ermolova N.V. Pregnancy and cervical cancer. Chief Physician of the South of Russia. 2022; 2(83): 25-8. (in Russian)].
  9. Rey Valzacchi G.M., Odetto D., Saadi J.M., Zamora L.B., Loza C., Medina M. et al. Conservative treatment of cervical cancer: A single center experience over a two-decade period. Gynecol. Oncol. Rep. 2023; 48: 101226. https:// dx.doi.org/10.1016/j.gore.2023.101226.
  10. Kacerovsky M., Musilova I., Baresova S., Kolarova K., Matulova J., Wiik J. et al. Cervical excisional treatment increases the risk of intraamniotic infection in subsequent pregnancy complicated by preterm prelabor rupture of membranes. Am. J. Obstet. Gynecol. 2023; 229(1): 51.e1-51.e13. https:// dx.doi.org/10.1016/j.ajog.2022.12.316.
  11. Han L., Chen Y., Zheng A., Chen H. Effect of preoperative cervical conization before hysterectomy on survival and recurrence of patients with cervical cancer: A systematic review and meta-analysis. Gynecol. Oncol. 2023; 174: 167-74. https://dx.doi.org/10.1016/j.ygyno.2023.05.004.
  12. Terzic M., Makhadiyeva D., Bila J., Andjic M., Dotlic J., Aimagambetova G. et al. Reproductive and obstetric outcomes after fertility-sparing treatments for cervical cancer: current approach and future directions. J. Clin. Med. 2023; 12(7): 2614. https://dx.doi.org/10.3390/jcm12072614.
  13. Hashiramoto S., Kinjo T., Tanaka S.E., Arai W., Shimada M., Ashikawa K. et al. Vaginal microbiota and pregnancy outcomes of patients with conization histories. J. Womens Health (Larchmt). 2023; 32(3): 375-84. https://dx.doi.org/10.1089/jwh.2022.0440.
  14. Коган Е.А., Файзулина Н.М., Исраилова А.Х., Козаченко А.В., Демура Т.А., Темишева Я.А., Екимов А.Н., Донников А.Е. Мониторинг больных, перенесших операцию конизации шейки матки по поводу цервикальной интраэпителиальной неоплазии (клинико-морфологические и молекулярно-биологические аспекты проблемы). Акушерство и гинекология. 2012; 1: 70-4. [Kogan E.A., Faizulina N.M., Israilova A.Kh., Kozachenko A.V., Demura T.A., Temisheva Ya.A., Ekimov A.N., Donnikov A.E. Monitoring patients undergoing conization of the cervix uteri for cervical intraepithelial neoplasia: Clinical, morphological, and molecular biological aspects. Obstetrics and Gynecology. 2012; (1): 70-4. (in Russian)].
  15. Аганезова Н.В., Аганезов С.С., Шило М.М. Миома матки: современные практические аспекты заболевания. Проблемы репродукции. 2022; 28(4): 97-105. [Aganezova N.V., Aganezov S.S., Shilo M.M. Uterine fibroids: modern practical aspects of the disease. Russian Journal of Human Reproduction. 2022; 28(4): 97-105. (in Russian)]. https://dx.doi.org/10.17116/repro20222804197.
  16. Чуруксаева О.Н., Коломиец Л.А., Савенкова О.В., Недосеков В.В., Ибрагимова М.К. Прогностическое значение Ki67, циклооксигеназы-2 (COX-2) и p16ink4a у больных местнораспространенным раком шейки матки. Сибирский онкологический журнал. 2016; 15(5): 25-32. [Churuksaeva O.N., Kolomiets L.A., Savenkova O.V., Nedosekov V.V., Ibragimova M.K. Prognostic significance of Ki67, cyclooxygenase-2 (COX-2) and p16ink4a in patients with locally advanced cervical cancer. Siberian Journal of Oncology. 2016; 15(5): 25-32. (in Russian)]. https://dx.doi.org/10.21294/ 1814-4861-2016-15-5-25-32.
  17. Hermans K.E.P.E., van den Brandt P.A., Loef C., Jansen R.L.H., Schouten L.J. Adherence to the World Cancer Research Fund and the American Institute for Cancer Research lifestyle recommendations for cancer prevention and cancer of unknown primary risk. Clin. Nutr. 2022; 41(2): 526-35. https://dx.doi.org/10.1016/j.clnu.2021.12.038.
  18. Лапочкина Н.П., Джалалова П.М., Ротару Т.В. Изменения микроциркуляции слизистой оболочки шейки матки при предраковых заболеваниях. Вестник ИвГМА. 2021; 26(1): 40-3. [Lapochkina N.P., Jalalova P.M., Rotaru T.V. Microcirculation alterations in cervical mucosa in precancerous diseases. Bulletin of Ivanovo State Medical Academy. 2021; 26(1): 40-3. (in Russian)]. https://dx.doi.org/10.52246/1606-8157_2021_26_1_40.
  19. Никитаева А.П., Росюк Е.А., Вишнева Е.М. Влияние гестационной артериальной гипертензии на течение беременности и развитие осложнений со стороны матери и плода. Современные проблемы науки и образования. 2023; 4: 118-20. [Nikitaeva A.P., Rosyuk E.A., Vishneva E.M. The effect of gestational hypertension on the course of pregnancy and the development of maternal and fetal complications. Modern Problems of Science and Education. 2023; (4): 118-20. (in Russian)]. https://dx.doi.org/10.17513/spno.32862.
  20. Кононова И.Н., Рогачева Т.В. Проблема клинико-психологического сопровождения пациенток с патологией шейки матки. Медицинская психология в России. 2015; 1(30): 10. [Kononova I.N., Rogacheva T.V. The issue of the clinical and psychological support of patients with cervical pathology. Medical psychology in Russia. 2015; 1(30): 10. (in Russian)].
  21. Мочалова М.Н., Рындин В.И., Мудров В.А. Последствия травмы шейки матки как медицинская и социальная проблема. Российский вестник акушера-гинеколога. 2022; 22(6): 35-41. [Mochalova M.N., Ryndin V.I., Mudrov V.A. Consequences of cervical trauma as a medical and social problem. Russian Bulletin of Obstetrician-Gynecologist. 2022; 22(6): 35 41. (in Russian)]. https://dx.doi.org/10.17116/rosakush20222206135.
  22. Зиганшин А.М., Кулавский В.А., Нагимова Э.М., Шакиров А.Р., Адигамова Г.С. Материнская смертность от послеродовых кровотечений. Медицинский вестник Башкортостана. 2019; 6(84): 53-7. [Ziganshin A.M., Kulavskiy V.A., Nagimova E.M., Shakirov A.R., Adigamova G.S. Maternal mortality from postpartum haemorrhage. Bashkortostan Medical Journal. 2019; 14(6): 53-7. (in Russian)].
  23. Бебнева Т.Н., Ковалев В.В., Лаврентьева И.В., Исламиди Д.К. Особенности структуры патологии шейки матки у беременных женщин. Уральский медицинский журнал. 2018; (13): 18-21. [Bebneva T.N., Kovaliov V.V., Lavrentieva I.V., Islamidi D.K. Features of the structure of the cervix pathology in pregnant women. Ural Medical Journal. 2018; (13): 18-21. (in Russian)]. https://dx.doi.org/10.25694/URMJ.2018.13.41.

Қосымша файлдар

Қосымша файлдар
Әрекет
1. JATS XML

© Bionika Media, 2024

Осы сайт cookie-файлдарды пайдаланады

Біздің сайтты пайдалануды жалғастыра отырып, сіз сайттың дұрыс жұмыс істеуін қамтамасыз ететін cookie файлдарын өңдеуге келісім бересіз.< / br>< / br>cookie файлдары туралы< / a>