The first experience of using an innovative diode laser in the treatment of genitourinary syndrome of menopause

Мұқаба

Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Рұқсат ақылы немесе тек жазылушылар үшін

Аннотация

Genitourinary syndrome of menopause (GSM) refers to a collection of symptoms including dryness, itching, burning, dyspareunia, and frequent recurrent urinary tract infections that occur in postmenopausal women and significantly impair their quality of life, emotional and mental health, and sexual function. Traditionally, local or systemic hormonal therapy aimed at increasing estrogen levels is administered, but not all patients may benefit from it. Laser treatment, including the use of a diode laser, can be an effective and safe alternative.

Objective: To obtain additional data on the safety and effectiveness of the diode laser in treating patients with GSM.

Materials and methods: Twenty-nine patients received laser therapy using the Lasemar 1500 diode device (1470-nm wavelength) once every two weeks for a total of four sessions. The effectiveness was assessed using the Vaginal Health Index (VHI) and the Female Sexual Function Index (FSFI).

Results: The mean VHI score increased from 15.2 to 21.2 after treatment. The VHI score increased by more than 3 points in 27 patients (93%), thus confirming the clinical significance of the changes. There was a considerable increase in the total FSFI score in sexually active patients (n=18), from 16.9 to 28.1. Three patients reported on the resumption of sexual activity after treatment. The procedures were tolerated well by all patients and no serious adverse events were noted.

Conclusion: The results of the observational study of 29 patients showed the effectiveness and safety of using the diode laser for the correction of GSM symptoms in 27 patients. However, the absence of a control group and the limited number of participants make it necessary to continue further research.

Толық мәтін

Рұқсат жабық

Авторлар туралы

Aina Saidova

Academician V.I. Kulakov National Medical Research Centre for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia

Хат алмасуға жауапты Автор.
Email: a_saidova@oparina4.ru
ORCID iD: 0000-0003-3473-3109

PhD, obstetrician-gynecologist at the Department of Aesthetic Gynecology and Rehabilitation

Ресей, Moscow

Inna Apolikhina

Academician V.I. Kulakov National Medical Research Centre for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia; I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia

Email: i_apolikhina@oparina4.ru
ORCID iD: 0000-0002-4581-6295

Dr. Med. Sci., Professor, Head of the Department of Aesthetic Gynecology and Rehabilitation, V.I. Kulakov NMRC for AG&P, Ministry of Health of Russia; Professor of the Department of Obstetrics, Gynecology, Perinatology and Reproductology, Institute of Vocational Education, I.M. Sechenov First MSMU, Ministry of Health of Russia (Sechenov University)

Ресей, Moscow; Moscow

Әдебиет тізімі

  1. Nappi R.E., Kokot-Kierepa M. Vaginal health: insights, views & attitudes (VIVA) - results from an international survey. Climacteric. 2012; 15(1): 36-44. https://dx.doi.org/10.3109/13697137.2011.647840.
  2. Management of symptomatic vulvovaginal atrophy: 2013 position statement of the North American Menopause Society. Menopause. 2013; 20(9): 888-902; quiz 903-4. https://dx.doi.org/10.1097/GME.0b013e3182a122c2.
  3. Ермакова Е.И., Балан В.Е., Тихомирова Е.В., Лазарева И.Н., Лапина А.В., Панина Е.М. Генитоуринарный менопаузальный синдром: диагностика и принципы лечения (краткие клинические рекомендации). Российский вестник акушера-гинеколога. 2017; 17(6): 89-95. [Ermakova E.I., Balan V.E., Tikhomirova E.V., Lazareva I.N., Lapina A.V., Panina E.M. Genitourinary syndrome of menopause: diagnosis and principles of treatment (brief clinical recommendations). Russian Bulletin of Obstetrician-Gynecologist. 2017; 17(6): 89-95. (in Russian)]. https://dx.doi.org/10.17116/rosakush201717689-95.
  4. Phillips N.A., Bachmann G.A. The genitourinary syndrome of menopause. Menopause. 2021; 28(5): 579-88. https://dx.doi.org/10.1097/GME.0000000000001728.
  5. Li J., Liu F., Liu Z., Li M., Wang Y., Shang Y. et al. Prevalence and associated factors of depression in postmenopausal women: a systematic review and meta-analysis. BMC Psychiatry. 2024; 24(1): 431. https://dx.doi.org/10.1186/s12888-024-05875-0.
  6. Pickar J.H. Emerging therapies for postmenopausal vaginal atrophy. Maturitas. 2013; 75(1): 3-6. https://dx.doi.org/10.1016/j.maturitas.2013.01.020.
  7. Sturdee D.W., Panay N.; International Menopause Society Writing Group. Recommendations for the management of postmenopausal vaginal atrophy. Climacteric. 2010; 13(6): 509-22. https://dx.doi.org/10.3109/ 13697137.2010.522875.
  8. La Rosa V.L., Ciebiera M., Lin L.T., Fan S., Butticè S., Sathyapalan T. et al. Treatment of genitourinary syndrome of menopause: the potential effects of intravaginal ultralow-concentration oestriol and intravaginal dehydroepiandrosterone on quality of life and sexual function. Prz Menopauzalny. 2019; 18(2): 116-22. https://dx.doi.org/10.5114/pm.2019.86836.
  9. Shifren J.L. Genitourinary syndrome of menopause. Clin. Obstet. Gynecol. 2018; 61(3): 508-16. https://dx.doi.org/10.1097/GRF.0000000000000380.
  10. Norton P., Brubaker L. Urinary incontinence in women. Lancet. 2006; 367(9504): 57-67. https://dx.doi.org/10.1016/S0140-6736(06)67925-7.
  11. Fistonić N., Fistonić I., Guštek Š.F., Turina I.S., Marton I., Vižintin Z. et al. Minimally invasive, non-ablative Er:YAG laser treatment of stress urinary incontinence in women--a pilot study. Lasers Med. Sci. 2016; 31(4): 635-43. https://dx.doi.org/10.1007/s10103-016-1884-0.
  12. Аполихина И.А., Малышкина Д.А., Бычкова А.Е., Паузина О.А. Применение неодимового лазера в практике акушера-гинеколога. Акушерство и гинекология. 2021; 1: 194-9. [Apolikhina I.A., Malyshkina D.A., Bychkova A.E., Pauzina O.A. Use of neodymium laser in the practice of an obstetrician/gynecologist. Obstetrics and Gynecology. 2021; (1): 194-9. (in Russian)]. https://dx.doi.org/10.18565/aig.2021.1.194-199.
  13. Dodero D., Frascani F., Angelucci M., Bernabei G., Merlo E., Locatelli F. et al. Solid state vaginal laser for the treatment of genitourinary syndrome of menopause: a preliminary report. Open Journal of Obstetrics and Gynecology. 2018; 08(02): 113-21. https://dx.doi.org/10.4236/ojog.2018.82015.
  14. Barba M., Cola A., De Vicari D., Costa C., Castelli A.P., Volontè S. et al. Efficacy of a diode vaginal laser in the treatment of the genitourinary syndrome of menopause. Bioengineering. 2023; 10(10): 1158. https://dx.doi.org/10.3390/bioengineering10101158.
  15. Filippini M., Porcari I., Ruffolo A.F., Casiraghi A., Farinelli M., Uccella S. et al. CO2-Laser therapy and genitourinary syndrome of menopause: a systematic review and meta-analysis. J. Sex. Med. 2022; 19(3): 452-70. https:// dx.doi.org/10.1016/j.jsxm.2021.12.010.
  16. Giarenis I., Tsiapakidou S., Zacche M., Mukhopadhyay S., Mahmood T. European Board and College of Obstetrics and Gynaecology (EBCOG) position statement on the use of laser vaginal devices for treatment of genitourinary syndrome of menopause, vaginal laxity, pelvic organ prolapse and stress urinary incontinence. Eur. J. Obstet. Gynecol. Reprod. Biol. 2024: 299: 342-4. https://dx.doi.org/10.1016/j.ejogrb.2024.05.021.
  17. Zipper R., Lamvu G. Vaginal laser therapy for gynecologic conditions: re-examining the controversy and where do we go from here. J. Comp. Eff. Res. 2022; 11(11): 843-51. https://dx.doi.org/10.2217/cer-2021-0281.

Қосымша файлдар

Қосымша файлдар
Әрекет
1. JATS XML
Жүктеу
2. Fig. 1. Average IVZ score before and after laser treatment

Жүктеу (35KB)
Метадеректер
3. Fig. 2. Average score of the IZHSF before and after laser treatment

Жүктеу (34KB)
Метадеректер

© Bionika Media, 2024

Осы сайт cookie-файлдарды пайдаланады

Біздің сайтты пайдалануды жалғастыра отырып, сіз сайттың дұрыс жұмыс істеуін қамтамасыз ететін cookie файлдарын өңдеуге келісім бересіз.< / br>< / br>cookie файлдары туралы< / a>